Results 201 to 210 of about 19,795 (292)

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, Volume 13, Issue 18, 27 March 2026.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

GHz dynamic holographic VCSEL chip via current-addressed modes multiplexing. [PDF]

Nat Commun
Hu X, Dong Y, Shi J, Li B, Luan H, Chi N, Gu M, Fang X.   +7 more
europepmc   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

Advanced Science, Volume 13, Issue 17, 23 March 2026.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si   +10 more
wiley   +1 more source

Coherent optical interconnects using Fermat number transform and hollow core fibre. [PDF]

Commun Eng
Chen S, Liu Z, Zhao C, Zhang M, Li P, Zhang L, Luo J, Hu Z, Chen C, Hua X, Liao X, Zhao Z, Tang M.   +12 more
europepmc   +1 more source

Recent Advances in Decoupling Strategies for Soft Sensors

Advanced Science, Volume 13, Issue 17, 23 March 2026.
This review provides an overview of recent advances in decoupling strategies for soft sensors. It summarizes single‐modal sensors that are insensitive to stretching, bending, crosstalk, and other environmental interferences, and highlights emerging multimodal decoupling methods enabled by spatiotemporal information and machine learning.
Yangbo Yuan, Wanqing Zhang, Jia‐Yu Yang, Manqi Peng, Huanyu Cheng   +4 more
wiley   +1 more source

All-optical temporal integration mediated by subwavelength heat antennas. [PDF]

Nat Commun
Zhang Y, Farmakidis N, Roumpos I, Moralis-Pegios M, Tsakyridis A, Lee JS, Dong B, He Y, Aggarwal S, Pleros N, Bhaskaran H.   +10 more
europepmc   +1 more source

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen, Longtao Huangfu, Gangjian Wang, Xueying Wang, Huanbo Zhu, Qian Yao, Cong Chen, Xiaohuan Tang, Ting Guo, Biao Fan, Xingyang Liu, Qingda Li, Zining Liu, Ying Hu, Tianze Sun, Jiafu Ji, Xiaofang Xing   +16 more
wiley   +1 more source

OAM multiplication operator enabled holographic multiplexing. [PDF]

Light Sci Appl
Shen F, Mao Z, Fan W, Wu J, Fang Z, Liu H, Chen X, Zhang Y, Chen Y.   +8 more
europepmc   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source