Results 101 to 110 of about 1,148,835 (372)
Molecular Oncology, EarlyView.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
wiley +1 more source
Frontiers in Physics, 2022 In this study, we propose a quantitative technique to analyze and evaluate microstructures of skin hair follicles based on Mueller Matrix transmission microscopy.
Yixuan Shi +18 more
doaj +1 more source
Annals of Pure and Applied Logic, 2003 We generalize the intuitionistic Hyland–Ong games (and in a second step Abramsky–Jagadeesan–Malacaria games) to a notion of polarized games allowing games with plays starting by proponent moves. The usual constructions on games are adjusted to fit this setting yielding game models for both Intuitionistic Linear Logic and Polarized Linear Logic.
openaire +3 more sources
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
MIF as an oncogenic driver of low‐heterogeneity melanomas
Molecular Oncology, EarlyView.Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran +4 more
wiley +1 more source
Developmental Cell, 2005 Three current papers in Cell and in this issue of Developmental Cell highlight the role of the exocyst in recycling of membrane proteins from endosomes to the plasma membrane in asymmetric cell division and polarized epithelial cells.
Somers, W. Gregory., Chia, William.
openaire +2 more sources
Role of Human Macrophage Polarization in Inflammation during Infectious Diseases
International Journal of Molecular Sciences, 2018 Experimental models have often been at the origin of immunological paradigms such as the M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in animal models is not as obvious in humans, and the separating line between M1 ...
C. Atri, F. Guerfali, D. Laouini
semanticscholar +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Characterization of apartments in polar Grassmannians [PDF]
arXiv, 2011 Buildings of types $\textsf{C}_n$ and $\textsf{D}_n$ are defined by rank $n$ polar spaces. The associated building Grassmannians are polar and half-spin Grassmannians. Apartments in dual polar spaces and half-spin Grassmannians were characterized in \cite{CKS}.
arxiv
Macrophage Polarization in Physiological and Pathological Pregnancy
Frontiers in Immunology, 2019 The immunology of pregnancy is complex and poorly defined. During the complex process of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in the maintenance of maternal-fetal tolerance.
Yongli Yao, Xiang-Hong Xu, Liping Jin
semanticscholar +1 more source