Results 41 to 50 of about 2,172,741 (304)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Novel Base Station MIMO Antennas with Enhanced Spectral Efficiencies Using Angular Reuse

International Journal of Antennas and Propagation, 2015
The true polarization diversity (TPD) technique is combined with the spatial diversity technique in novel MIMO antenna array geometries with a large number of elements.
Miguel Mora-Andreu, David A. Sánchez-Hernández   +1 more
doaj   +1 more source

Coherent polarization shift keying modulated free space optical links over a Gamma-Gamma turbulence channel [PDF]

, 2011
Problem statement: The optical signal propagating through the Free Space Optical (FSO) channel suffers from irradiance and phase fluctuations caused by the atmospheric turbulence, which results in Bit Error Rate (BER) performance degradation ...
Ghassemlooy, Zabih, Popoola, Wasiu Oyewole, Popoola, Wasiu O., Tang, Xuan, Rajbhandari, Sujan, Lee, Chung Ghiu, Ghassemlooy , Zabih, Lee , Chung Ghiu   +7 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Wavelength-diverse polarization modulators for Stokes polarimetry [PDF]

Applied Optics, 2010
Information about the three-dimensional structure of solar magnetic fields is encoded in the polarized spectra of solar radiation by a host of physical processes. To extract this information, solar spectra must be obtained in a variety of magnetically sensitive spectral lines at high spatial, spectral, and temporal resolution with high precision.
Tomczyk, Steven, Casini, Roberto, de Wijn, Alfred G., Nelson, Peter G.   +3 more
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Trade-Off Analysis of Mutual Coupling Effect on MIMO Antenna Multiplexing Efficiency in Three-Dimensional Space

IEEE Access, 2018
We analyzed the relation between two opposite effects of mutual coupling (MC), correlation reduction and gain loss, on the MIMO antenna performance in three-dimensional (3D) space. In the antenna level, those MC effects can be represented in terms of two
Satya Nandiwardhana, Jae-Young Chung
doaj   +1 more source

Silicon photonic circuit with polarization diversity

Optics Express, 2008
We devised a silicon photonic circuit with polarization diversity that consists of polarization splitters and polarization rotators. The splitter is based on a simple directional coupler and the rotator has an off-axis double-core structure. Both devices can be made by using planar fabrication technology and require no complex proceses for the ...
Hiroshi, Fukuda, Koji, Yamada, Tai, Tsuchizawa, Toshifumi, Watanabe, Hiroyuki, Shinojima, Sei-Ichi, Itabashi   +5 more
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source