Results 241 to 250 of about 2,216,221 (313)

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

Advanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi, Minying Low, Peng Xiu, Kresten Lindorff‐Larsen, Yong Wang   +4 more
wiley   +1 more source

From Participation to Evidence: Listening-Informed Policies and the Epistemic Role of Lived Experience in Population Health. [PDF]

Health Expect
Barello S, Monaci M, Bigi S, Credi B, Korenjak M.   +4 more
europepmc   +1 more source

Large Language Model‐Informed Dual‐Track AI Framework for the Synergistic Design of Crack‐Free and High‐Strength Superalloys

Advanced Science, EarlyView.
This paper illustrates a knowledge‐augmented dual‐track AI framework for advanced superalloy design. First, Large Language Models translate metallurgical heuristics into explicit rules to rapidly prune a vast compositional search space. Subsequently, LLM‐distilled priors safely guide a reinforcement learning agent during autonomous process optimization,
Jian Yao, Junkang Wu, Jie Su, Fuzhu Wang, Zi Wang, Li Wang, Liming Tan, Lan Huang, Feng Liu, Yong Liu   +9 more
wiley   +1 more source

Shaping food system governance: mapping the national food and nutrition legislation landscape across Europe. [PDF]

Front Public Health
Scarsi N, Taha A, Lacalaprice D, Perazzoni G, Soru L, Grande SD, D'Anna D, Staffieri A, Geantǎ M, Pastorino R, Villani L, Boccia S.   +11 more
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

US State Policy Index for Population Health Analyses. [PDF]

Milbank Q
Montez JK, Gutin I, Monnat SM.
europepmc   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Journal research data policies in materials science.

Digit Discov
Hörmann L, Myneni H, Al-Hamd RKS, Batalović K, Bonfanti S, Grasselli F, Gražulis S, Koç B, Konstantinou K, Lončarić I, Lopanitsyna N, Oliveira JM, Pegolo P, Ramos P, Rossi K, Schwaminger SP, Simmen E, Todorović M, Stricker M, Schmidt J.   +19 more
europepmc   +1 more source

Policy monitoring indexes targeting non-communicable diseases: protocol for a scoping review. [PDF]

BMJ Open
Bjørnarå HB, Flodgren GM, Helleve A.
europepmc   +1 more source