Results 51 to 60 of about 6,859,275 (285)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The rapid rollout of Israel’s vaccination program has led to considerable international interest. In this brief commentary we consider how the criteria for vaccination priority groups differ between Israel and selected European countries.
Jonathan Cylus +2 more
doaj +1 more source
Industrial waste management within manufacturing: a comparative study of tools, policies, visions and concepts [PDF]
Industrial waste is a key factor when assessing the sustainability of a manufacturing process or company. A multitude of visions, concepts, tools, and policies are used both academically and industrially to improve the environmental effect of ...
Bjelkemyr, Marcus +4 more
core
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Przegląd, zmiany, reformy – zmiany polityki regionalnej w Unii Europejskiej i w Norwegii
Reforma unijnej polityki spójności na lata 2007–2013 wpłynęła na zmiany w działaniach dostosowawczych podejmowanych w państwach członkowskich. Zmiany te – jak dowodzi analiza przeprowadzona dla UE 15, nowych państw członkowskich (ze szczególnym ...
Douglas Yuill +2 more
doaj
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Online Learning and Emergency Remote Teaching: Opportunities and Challenges in Emergency Situations
The aim of the study is to analyse the opportunities and challenges of emergency remote teaching based on experiences of the COVID-19 emergency. A qualitative research method was undertaken in two steps.
Fernando Ferri +2 more
doaj +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Innovations and Support Institutions: the 1st Geographical Indication in Brazil
The Geographical Indication (GI) is an intellectual property instrument that may allow the adoption of innovations through the appreciation and insertion of origin labeled products in the market.
Yohanna Vieira Juk, Marcos Paulo Fuck
doaj +1 more source
Exploring personalized life cycle policies [PDF]
Ambient Intelligence imposes many challenges in protecting people's privacy. Storing privacy-sensitive data permanently will inevitably result in privacy violations.
Anciaux, N.L.G. +3 more
core +2 more sources

