Results 241 to 250 of about 2,687,427 (314)

Quantitative evaluation and optimization of AI policy and regulatory texts for smart healthcare. [PDF]

Front Public Health
Zhou Z, Xiang Y, Liu C, Huang X, Fu Y.
europepmc   +1 more source

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

Correction to: Can medical consortiums bridge the gap in health inequity in China? A propensity score matching analysis. [PDF]

Health Policy Plan
europepmc   +1 more source

Adapting WHO integrated care for older people (ICOPE) models to the Korean context: Policy relevance and feasibility-a Delphi survey. [PDF]

JAR Life
Kim HS, Won CW, Lee Y.
europepmc   +1 more source

Optimal Active Debris Removal mission planning to inform policy decisions

Nihal Simha, Simone Servadio, Miles Lifson, Giovanni Lavezzi, Richard Linares   +4 more
openalex   +1 more source

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

Advanced Science, EarlyView.
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang, Yuxin Yang, William Martin, Kingsten Lin, Zixu Wang, Cheng‐Chang Lu, Weiwen Jiang, Ruth Nussinov, Joseph Loscalzo, Qiang Guan, Feixiong Cheng   +10 more
wiley   +1 more source

Advancing real-world data integration in nursing research: A policy perspective on Japan's next-generation medical infrastructure law and the EU EHDS framework. [PDF]

Jpn J Nurs Sci
Kubota K, Ishibashi S.
europepmc   +1 more source

Study on the policy implementation of the Guangdong-Hong Kong-Macao joint graduate training program and regional talent development. [PDF]

PLoS One
Li S, Lam JFI.
europepmc   +1 more source

From Research Influencers to Substance Use Policymakers: Bibliometrics Demonstrate Translation from Research to Policy. [PDF]

J Stud Alcohol Drugs
Llewellyn NM, Weber A, Kegley S, Nehl EJ, Abraham AJ.   +4 more
europepmc   +1 more source

LG-H-PPO: offline hierarchical PPO for robot path planning on a latent graph. [PDF]

Front Robot AI
Han X.
europepmc   +1 more source