Results 51 to 60 of about 10,007,732 (312)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Encouraging Future Innovation: Youth Entrepreneurship Education [PDF]
, 2005 [Excerpt] Entrepreneurs drive America’s economy, accounting for the majority of our nation’s new job creation and innovations. According to the U. S. Census Bureau’s 2002 Survey of Business Owners, self-employed individuals who have no paid employees ...
Office of Disability Employment Policy
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Workforce Intermediaries: Strategic Connections For Youth With Disabilities [PDF]
, 2005 [Excerpt] Over the last two decades, landmark legislation, successful initiatives and technological advances have helped improve employment opportunities for people with disabilities.
Office of Disability Employment Policy
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Workplace Accommodations: Low Cost, High Impact [PDF]
, 2007 [Excerpt] All employees need the right tools and work environment to effectively perform their jobs. Similarly, individuals with disabilities may need workplace adjustments — or accommodations — to maximize the value they can add to their employer ...
Office of Disability Employment Policy
core +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Increasing Options: The Ticket To Work And Self-Sufficiency Program [PDF]
, 2005 [Excerpt] The Ticket to Work and Self-Sufficiency Program is an avenue to employment for people with disabilities who want to join or reenter the workforce.
Office of Disability Employment Policy
core +1 more source
Policy Science and Health Policy.
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 2001 Policy science provides the analytical frameworks to examine (1) the process of policy formation and implementation (Issue definition, Agenda setting, Alternative development, Decision and implementation, and Appraisal); (2) the initial and final shapes of policy content (Temporal and special distribution of costs and benefits, Selection of ...
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source