Results 81 to 90 of about 1,108,565 (268)
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus +2 more
wiley +1 more source
Wildlife killer instincts: human wildlife conflict and fatal incidents in Botswana
This study adopted a mixed methods explanatory sequential research design to investigate predictors of the increased probability of human-wildlife conflicts (HWC) resulting in human injuries and fatalities. The first phase of the study involved analyzing
Israel R. Blackie +2 more
doaj +1 more source
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Health Policy Analysis - An Introduction
This book is intended for students, teachers, and educators interested in health policymaking. A key theme in the book is that health policymaking includes more than translating empirical knowledge about the determinants of health and disease into effective policy measures. A linear path from knowledge to health policy does not exist.
openaire +1 more source
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon +9 more
wiley +1 more source
Impacts of efficiency on food security status of smallholders in the Gurage Zone of Ethiopia
The lower productivity in the agricultural sector has been one of the main contributors to the Ethiopia’s food insecurity. Despite less than expected outcomes, the government is nevertheless placing a high priority on ensuring food security through large
Gizachew Argaw +3 more
doaj +1 more source
Hospital Choice for Cataract Treatments: The Winner Takes Most [PDF]
Background Transparency in quality of care is an increasingly important issue in healthcare. In many international healthcare systems, transparency in quality is crucial for health insurers when purchasing care on behalf of their consumers, for ...
Suzanne Ruwaard, Rudy C M H Douven
doaj
Understanding Economic Evaluation: A Policy Perspective for Clinicians
The rhetoric of ‘efficiency’ frames much current debate about how limited health care resources should be used. Clinicians increasingly turn to economic evaluation literature to discern evidence-based claims of ‘efficiency’ or ‘cost effectiveness’ from ...
M Giacomini, J Hurley
doaj +1 more source
Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky +5 more
wiley +1 more source

