Results 21 to 30 of about 3,003,767 (295)

Vaccination against Foot-and-mouth disease : do initial conditions affect its benefit? [PDF]

, 2013
When facing incursion of a major livestock infectious disease, the decision to implement a vaccination programme is made at the national level. To make this decision, governments must consider whether the benefits of vaccination are sufficient to ...
A Bouma, AI Donaldson, AI Donaldson, AP Galvani, CP Jewell, D Schley, EM Cottam, FHM Tomassen, George J. Gunn, GJ Boender, Harriet K. Auty, I Traulsen, JA Backer, JC Gibbens, K Orsel, KB Parent, M Kobayashi, M Quan, Mark E. J. Woolhouse, ME Arnold, Michael J. Tildesley, MJ Keeling, MJ Keeling, MJ Morelli, MJ Tildesley, MJ Tildesley, MJ Tildesley, MJ Tildesley, MJ Tildesley, MJ Tildesley, N Savill, NT Brewer, PR Bessell, PR Bessell, PV Barnett, S Alexandersen, Thibaud Porphyre, TW Bates, Vittoria Colizza   +38 more
core   +6 more sources

Implementation of a cardiovascular toolkit in primary care increased women Veterans’ engagement in behavior change programs: results from a non-randomized stepped wedge trial

BMC Primary Care
Background Cardiovascular (CV) disease is the leading cause of death among U.S. women, yet women have a limited understanding of their CV-related morbidity and mortality risks.
Melissa M. Farmer, Alison B. Hamilton, Erin P. Finley, Martin L. Lee, Catherine Chanfreau, Claire Than, Julian Brunner, C. Amanda Schweizer, Tannaz Moin, Bevanne Bean-Mayberry   +9 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

The Rapid Implementation Feedback (RIF) report: real-time synthesis of qualitative data for proactive implementation planning and tailoring

Implementation Science Communications
Background Qualitative methods are a critical tool for enhancing implementation planning and tailoring, yet rapid turn-around of qualitative insights can be challenging in large implementation trials. The Department of Veterans Affairs-funded EMPOWER 2.0
Erin P. Finley, Joya G. Chrystal, Alicia R. Gable, Erica H. Fletcher, Agatha Palma, Ismelda Canelo, Rebecca S. Oberman, La Shawnta S. Jackson, Rachel Lesser, Tannaz Moin, Bevanne Bean-Mayberry, Melissa M. Farmer, Alison Hamilton   +12 more
doaj   +1 more source

Organizational readiness to change as a leverage point for improving safety: a national nursing home survey

BMC Health Services Research, 2021
Background A stronger safety climate in nursing homes may reduce avoidable adverse events. Yet efforts to strengthen safety climate may fail if nursing homes are not ready to change.
Emma D. Quach, Lewis E. Kazis, Shibei Zhao, Pengsheng Ni, Valerie A. Clark, Sarah E. McDannold, Christine W. Hartmann   +6 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Collaborative tailoring of the Reach Out, Stay Strong Essentials (ROSE) program for pregnant veterans in the U.S. Veterans Health Administration: a qualitative case study of contextual conditions and adaptations

BMC Health Services Research
Background Reach Out, Stay Strong Essentials (ROSE) is an evidence-based intervention for preventing post-partum depression being implemented across U.S.
Erin P. Finley, Alison B. Hamilton, Ismelda Canelo, La Shawnta S. Jackson, Rachel Lesser, Rebecca S. Oberman, Julia Yosef, Joya G. Chrystal, Erica H. Fletcher, Bevanne Bean-Mayberry, Tannaz Moin, Melissa M. Farmer, Ariel J. Lang   +12 more
doaj   +1 more source

Beyond the Win: Pathways for Policy Implementation [PDF]

, 2016
When it comes to policy, a lot of attention is given to "the win." Whether it is something new and big like the Affordable Care Act, a piece of legislation in a large federal omnibus bill, or inclusion of critical language in a state policy, seeing the ...
Eritrea Habtemariam, Leonor Robles, Melanie Maltry, Sarah Stachowiak   +3 more
core  

Directed Security Policies: A Stateful Network Implementation

, 2014
Large systems are commonly internetworked. A security policy describes the communication relationship between the networked entities. The security policy defines rules, for example that A can connect to B, which results in a directed graph. However, this
Carle, Georg, Diekmann, Cornelius, Hupel, Lars   +2 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source