Results 41 to 50 of about 381,865 (264)

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Addressing conflict through collective action in natural resource management

International Journal of the Commons, 2017
The food security crisis and international “land grabs” have drawn renewed attention to the role of natural resource competition in the livelihoods of the rural poor.
Blake D Ratner, Ruth Meinzen-Dick, Jon Hellin, Everisto Mapedza, Jon Unruh, Wouter Veening, Eric Haglund, Candace May, Carl Bruch   +8 more
doaj   +1 more source

Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor‐Specific Outcomes in Adolescent and Young Adult Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek, Heleen Maurice‐Stam, Laura R. Beek, Jennifer van Dijk, Marjolein E. M. Langemeijer, Relinde W. Slooff‐Lentink, Alied M. van der Aa‐van Delden, Anne Westerweel, Marloes van Gorp, Hendrik W. B. Schreuder, Lianne M. Haveman, W. Peter Bekkering, Leonie G. Tigelaar, Johannes H. M. Merks, Martha A. Grootenhuis   +14 more
wiley   +1 more source

Racial differences in healthcare expenditures for prevalent multimorbidity combinations in the USA: a cross-sectional study

BMC Medicine, 2023
Background We aimed to model total charges for the most prevalent multimorbidity combinations in the USA and assess model accuracy across Asian/Pacific Islander, African American, Biracial, Caucasian, Hispanic, and Native American populations. Methods We
Manal Alshakhs, Patricia J. Goedecke, James E. Bailey, Charisse Madlock-Brown   +3 more
doaj   +1 more source

Policy Improvement Reinforcement Learning

CoRR
Reinforcement learning has become a central post-training paradigm for improving LLM and agent capabilities. Yet existing RL post-training methods share a common blind spot: they construct local learning signals from sampled trajectories, rewards, or feedback-conditioned targets, then update the policy without explicitly verifying whether the resulting
Wang, Huaiyang, Li, Xiaojie, Wang, Xiaohan, Zhang, Zhixia, Lu, Xiaodong, Huang, Zixuan, Chai, Jiajun, Yin, Guojun, Wang, Deqing, Zhou, Haoyi, Yang, Yaodong, Li, Jianxin, Ban, Yikun   +12 more
openaire   +2 more sources

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Shedding light on research participation effects in behaviour change trials: a qualitative study examining research participant experiences

BMC Public Health, 2016
Background The sequence of events in a behaviour change trial involves interactions between research participants and the trial process. Taking part in such a study has the potential to influence the behaviour of the participant, and if it does, this can
Virginia MacNeill, Marian Foley, Alan Quirk, Jim McCambridge   +3 more
doaj   +1 more source

Survival by Race and Ethnicity in Children and Adolescents/Young Adults With Relapsed/Refractory Hodgkin Lymphoma: A Pooled Analysis of Children's Oncology Group Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Despite 5‐year survival rates of over 90% among children and adolescents/young adults (CAYAs) with classic Hodgkin lymphoma (cHL), 15%–20% relapse after frontline therapy. Prior analysis of frontline Children's Oncology Group (COG) clinical trials demonstrated that, despite similar rates of relapse, non‐Hispanic Black (NHB) and ...
Mallorie B. Heneghan, Lindsay A. Renfro, Yue Wu, Katia M. Crisler, Erin Marcotte, Tanya Trippett, Terzah Horton, Bradford S. Hoppe, Frank G. Keller, Chris Forlenza, Cindy Schwartz, Kara M. Kelly, Peter D. Cole, Sharon M. Castellino, Justine M. Kahn   +14 more
wiley   +1 more source

Medical care epidemiology and unwarranted variation: the Israeli case

Israel Journal of Health Policy Research, 2017
In an article in this Journal, Mendlovic and colleagues report on regional variation in medical care across Israeli regions. This study joins a growing literature demonstrating generally high variation in the provision of health care services within ...
David C. Goodman, Andrew A. Goodman
doaj   +1 more source

Unlocking Data to Improve Public Policy

Communications of the ACM, 2019
Published as: Hastings JS, Howison M, Lawless T, Ucles J, White P. Unlocking Data to Improve Public Policy. Communications of the ACM 62(10): 48-53.
Justine S. Hastings, Mark Howison, Ted Lawless, John Ucles, Preston White, Research Improving People's Lives   +5 more
openaire   +2 more sources