Results 51 to 60 of about 7,955,412 (310)

Does poor methodological quality of prediction modeling studies translate to poor model performance? An illustration in traumatic brain injury

open access: yesDiagnostic and Prognostic Research, 2022
Background Prediction modeling studies often have methodological limitations, which may compromise model performance in new patients and settings. We aimed to examine the relation between methodological quality of model development studies and their ...
Isabel R. A. Retel Helmrich   +6 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

The Policy and Governance Observatory as a Facilitator of Smart and Evidence-based Governance [PDF]

open access: yesپژوهش‌های مدیریت عمومی
The complex and dynamic environment and the multiplicity of actors have made the nature of decision-making and policy-making in political systems complex and challenging. In order to face the challenges in this space and make decisions based on the facts,
Atiye Yousefi, Mahdi Abdolhamid
doaj   +1 more source

Acquiring core competencies in IKCO through elements of knowledge management: Investigating the mediation role of knowledge management processes [PDF]

open access: yesJournal of Information Technology Management, 2015
The purpose of this paper is to evaluate the effects of infrastructure and strategy of knowledge management on acquisition of core competencies through knowledge management process in ‘Iran Khodro Company’.
Abbas Monavarian   +2 more
doaj   +1 more source

Instrument constituencies and public policy-making: an introduction

open access: yes, 2018
For many years, policy-making has been envisioned as a process in which subsets of policy actors engage in specific types of interactions involved in the definition of policy problems, the articulation of solutions and their matching or enactment.
D. Béland   +2 more
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

The Patients’ Cost Analysis for Eye Care Services: An Investigation in Hospitals of Tehran [PDF]

open access: yesJournal of Health Management & Informatics, 2020
Background:The costs of the eye care services are considered as one of the most important obstacles to timely diagnosis and treatment of eye disorders, but there is  little evidence about patients’ cost for receiving these services. Objective: This paper
Nader Jahanmehr   +3 more
doaj  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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