Results 51 to 60 of about 8,532,846 (307)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

External consequences of public policy implementation based on social responsibility dimensions at the Universities of medical sciences

open access: yesSocial Determinants of Health, 2022
Background: The implementation of public policy in the presence of social responsibility dimensions is an opportunity to gain the support and trust of citizens.
Sakineh Ashrafi   +3 more
doaj   +1 more source

What makes policy complex?

open access: yesPolitical Science Research and Methods, 2020
AbstractPrevious research finds that policy complexity affects important political processes including legislative delegation and policy diffusion. However, policy complexity is not directly observable and the search for a reasonable proxy constitutes a major challenge for scholars.
openaire   +4 more sources

Integrating Palliative Care into the Health System in Lebanon [PDF]

open access: yes, 2018
K2P Policy Briefs bring together global research evidence, local evidence and context-specific knowledge to inform deliberations about health policies and programmes.
Souiedan, Sara   +2 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Promoting Effective School Policies for Childhood Overweight & Obesity Prevention in Lebanon [PDF]

open access: yes, 2019
K2P Policy Briefs bring together global research evidence, local evidence and context-specific knowledge to inform deliberations about health policies and programmes.
Saleh, Rana   +2 more
core  

Health Information System Policy 2023 [PDF]

open access: yes, 2023
The development of this first Health Information System (HIS) Policy is a result of various studies that have been undertaken to assess the functioning of Health Information and Management Information Systems in Kenya. These assessments identified a weak
Ministry of Public Health and Sanitation
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

The Policy and Governance Observatory as a Facilitator of Smart and Evidence-based Governance [PDF]

open access: yesپژوهش‌های مدیریت عمومی
The complex and dynamic environment and the multiplicity of actors have made the nature of decision-making and policy-making in political systems complex and challenging. In order to face the challenges in this space and make decisions based on the facts,
Atiye Yousefi, Mahdi Abdolhamid
doaj   +1 more source

Does poor methodological quality of prediction modeling studies translate to poor model performance? An illustration in traumatic brain injury

open access: yesDiagnostic and Prognostic Research, 2022
Background Prediction modeling studies often have methodological limitations, which may compromise model performance in new patients and settings. We aimed to examine the relation between methodological quality of model development studies and their ...
Isabel R. A. Retel Helmrich   +6 more
doaj   +1 more source

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