Results 51 to 60 of about 5,112,355 (300)
The 'policy-preferences model' : a new perspective on how researchers can facilitate the take-up of evidence by educational policy makers [PDF]
, 2012 The phrase ‘knowledge adoption’ refers to the often-complicated process by which policy makers ‘take on board’ evidence. While models have been put forward to explain this activity, this paper argues that such models are flawed and fail to fully address ...
Brown, Chris
core +3 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Policy Debates and Discourse Network Analysis: A Research Agenda
Politics and Governance, 2020 Discourse network analysis (DNA) is a combination of network analysis and qualitative content analysis. DNA has been applied to various policy processes and debates to show how policy actors are related at the discursive level, complementing coordination
Philip Leifeld
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Policy processes underpinning universal health insurance in Vietnam [PDF]
Global Health Action, 2014 Background: In almost 30 years since economic reforms or ‘renovation’ (Doimoi) were launched, Vietnam has achieved remarkably good health results, in many cases matching those in much higher income countries.
Bui T. T. Ha +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Global Health Action, 2023 Background The Framework Convention on Tobacco Control (FCTC) requires countries to develop and implement multi-sectoral tobacco control strategies, including policies and legislation.
Adam Silumbwe +4 more
doaj +1 more source
Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
Ecology and EvolutionIncreased imports of plants and timber through global trade networks provide frequent opportunities for the introduction of novel plant pathogens that can cross‐over from commercial to natural environments, threatening native species and ecosystem ...
Flora Donald +5 more
doaj +1 more source