Results 31 to 40 of about 86,937 (263)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Experimental-based energy performance evaluation of low-cost retrofit strategy for aging low-rise residential building for carbon neutrality

open access: yesCase Studies in Thermal Engineering, 2022
The CO2 reduction policy has driven the remodeling policy to reduce the energy consumption of buildings, which can be implemented by insulating and replacing windows to reduce the energy consumption of buildings.
Sungwoong Yang   +4 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

The effects of conventional and unconventional monetary policy on exchange rate volatility

open access: yesCogent Economics & Finance, 2021
This paper examines the impacts of U.S. conventional and unconventional monetary policy announcements on the volatility of six exchange rates, namely Australian dollar, British pound, Canadian dollar, Euro, Japanese yen, and Swiss franc against the U.S ...
Wan Wei, Susan Pozo
doaj   +1 more source

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

open access: yesArthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

Food security in Pakistan: Investigating the spillover effect of Russia-Ukraine conflict

open access: yesSustainable Futures
This is study investigates inter-connectedness of Russia-Ukraine conflict with wheat prices in Pakistan through oil prices, exchange rate, economic policy uncertainty.
Shujaat Abbas, Ibrahim Alnafrah
doaj   +1 more source

Efficient Data Stream Clustering With Sliding Windows Based on Locality-Sensitive Hashing

open access: yesIEEE Access, 2018
Data stream clustering over sliding windows generates clusters as the window moves. However, iterative clustering using all data in a window is highly inefficient in terms of memory use and computational load.
Jonghem Youn, Junho Shim, Sang-Goo Lee
doaj   +1 more source

Agenda-setting of tobacco control policy in Iran: a retrospective policy analysis study

open access: yesBMC Public Health, 2021
Background The prevalence of tobacco use, especially hookah, has increased in Iran In recent years, particularly among young people and women, and the age of onset of use has decreased.
Hamid Ravaghi   +5 more
doaj   +1 more source

Real‐world trends in prenatal antirheumatic drug utilization in Ontario, Canada: A cross‐sectional time‐series analysis

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

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