Results 21 to 30 of about 66,669 (176)

Characterisation of HIV‐1 Gag Cytotoxic T‐Lymphocyte Epitopes in the Southern African Region—A Systematic Review

Immunology, Volume 179, Issue 2, Page 165-184, October 2026.
Distribution of studies on HIV‐1 Gag cytotoxic T‐lymphocyte epitopes in the southern African region showing that the majority of studies (58.44%) were conducted in South Africa, followed by Botswana (15.58%), Zambia (10.39%), Malawi (7.79%), Zimbabwe (6.49%), and Angola (1.30%).
Tumelo L. Fortuin, Paballo Nkone, Shayne Loubser, Caroline T. Tiemessen, Simnikiwe H. Mayaphi   +4 more
wiley   +1 more source

The Involvement of the Cryptococcal Yeast Kexin Protease in the Proteolytic Activation of the Uncleaved Influenza Virus Hemagglutinin Glycoprotein

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
A haemagglutinin mimetic fluorogenic peptide assay revealed that recombinant Cryptococcus neoformans Kex2p exhibits strong haemagglutinin‐cleaving activity, suggesting a possible role for cryptococcal proteases in influenza virus activation. ABSTRACT Infectious diseases typically involve a single pathogen harming its host. However, in clinical settings,
Nolwazi F. Ntshangase, Khwezi Mdana, Nozethu Mjokane, Winschau F. van Zyl, Jacobus Albertyn, Olihile M. Sebolai   +5 more
wiley   +1 more source

Diverse Pathways and the Role of Timing: Youth Experiences of Leaving Care in China

Child &Family Social Work, Volume 31, Issue 3, Page 1931-1941, August 2026.
ABSTRACT In China, young people in state‐funded childcare institutions (Fuliyuan) are required to exit at age 18 unless still in education, compressing the move to adulthood. This study applies a life‐course lens to examine how the timing and sequencing of key life events shape care leavers' trajectories.
Shian Yin, Siobhan Laird, Lisa Warwick
wiley   +1 more source

Dysregulated Metabolism in People Living With HIV in the Modern ART‐Era: A Systematic Review of Targeted Metabolomics Studies

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy (ART) suppresses viral replication, it does not eradicate the virus, and metabolic dysregulation persists despite treatment.
Levanco K. Asia, Du Toit Loots, Shayne Mason, Esme Jansen Van Vuren, Monray E. Williams   +4 more
wiley   +1 more source

A Diagnostic Pitfall of Primary Aldosteronism Presenting as Recurrent Quadriparesis: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Quadriparesis refers to weakness affecting all four limbs. While most cases are neurogenic in origin, stemming from central or peripheral nervous system pathology, non‐neurogenic causes are less common and often under‐recognized. These include systemic or metabolic conditions that secondarily impair neuromuscular function.
Javed Shakir, Javeria Benyamin, Muhammad Usman Iqbal, Abdullah Sohail, Aafaq Mazhar, Hafiz Muhammad Abdullah, Erum Habib, Naseeb Danaf   +7 more
wiley   +1 more source

Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 6, June 2026.
ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode, Mitchel C. Rothholz, Stephan L. Foster, Erica R. Brody, John D. Gräbenstein   +4 more
wiley   +1 more source

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Guillain–Barré Syndrome After Malaria: A Case Report of a 7‐Year‐Old Child With Asymmetric Onset of Acute Motor Axonal Neuropathy

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT This case highlights that acute motor axonal neuropathy can present with asymmetric, relapsing weakness in children. In malaria‐endemic and resource‐limited settings, clinicians should consider atypical Guillain–Barré variants early, as timely recognition and treatment can significantly improve outcomes despite diagnostic and systemic ...
Muath Ibrahim Mohammed Abusaada, Mustafa Mohamed Ibrahim Ali, Muotaman Mohammed Abdalla Adam, Mohammed Hishameldeen Omer Ali, Mohamed Abdallah Mohamed Baraka, Amjad Ali Mohamedelhassan Bakheit, Khabab Abbasher Hussien Mohamed Ahmed, Isameldin Yousif Khidir Mohmed   +7 more
wiley   +1 more source

Africa's Struggle to Meet Global Pandemic Influenza Immunization Targets: Lessons for Public Health Policy and Preparedness—A Focus on Ghana

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Influenza remains a significant yet under‐prioritized public health challenge in Africa, where unique hurdles such as limited surveillance, variable seasonal patterns, and under‐resourced health systems constrain effective prevention and control. This commentary provides a detailed analysis of the influenza landscape, with a focused
Yula Salifu, Joseph Lasong, Ireneous Nangbeviel Dasoberi   +2 more
wiley   +1 more source

Mystery Disease X Outbreak in the Democratic Republic of the Congo: A Narrative Review of Epidemiological Patterns and Response Challenges

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims An unknown disease known as Disease X first surfaced in the Panzi Health Zone, Kwango Province, Democratic Republic of the Congo (DRC), towards the end of 2024. It mainly affected children under the age of five. The clinical characteristics and of the outbreak are examined in this review.
Muhammad Shaheer Bin Faheem, Muhammad Haroon‐Ul‐Rasheed, Sumaya Samadi   +2 more
wiley   +1 more source