Results 251 to 260 of about 86,994 (300)
Characteristics of four natural poliovirus type 1 variants with six-nucleotide deletion (2,783-2,788 nt) in the VP1 region. [PDF]
Lin J +15 more
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Annual Review of Genetics, 1993
INFECTIOUS eDNA AND IN VITRO SYNTHESIS OF INFECTIOUS VIRAL RNA 359 SELECTION AND GENERATION OF MUTANTS . . . . . . .... . . .. . . .. . . 360 Selection of Spontaneous Mutants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 Random Mutagenesis .... _ . . . . . . . _ _ .... ... ... _ _ . . . . . . . . . 370 Mutagenesis Targeted to Existing
Eckard Wimmer +2 more
openaire +3 more sources
INFECTIOUS eDNA AND IN VITRO SYNTHESIS OF INFECTIOUS VIRAL RNA 359 SELECTION AND GENERATION OF MUTANTS . . . . . . .... . . .. . . .. . . 360 Selection of Spontaneous Mutants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 Random Mutagenesis .... _ . . . . . . . _ _ .... ... ... _ _ . . . . . . . . . 370 Mutagenesis Targeted to Existing
Eckard Wimmer +2 more
openaire +3 more sources
2004
Poliovirus (PV) is the causal agent of paralytic poliomyelitis, an acute disease of the central nervous system (CNS). A killed and an oral live attenuated vaccine were both developed in the 1950s (Salk 1955; Sabin and Boulger 1973), and subsequent massive vaccination campaigns resulted in near total eradication of PV from most industrialized countries:
Blondel, B. +4 more
openaire +4 more sources
Poliovirus (PV) is the causal agent of paralytic poliomyelitis, an acute disease of the central nervous system (CNS). A killed and an oral live attenuated vaccine were both developed in the 1950s (Salk 1955; Sabin and Boulger 1973), and subsequent massive vaccination campaigns resulted in near total eradication of PV from most industrialized countries:
Blondel, B. +4 more
openaire +4 more sources
Biochemical and Biophysical Research Communications, 1972
Summary Poliovirus, dissociated by exposure to 9 M urea and 0.09 M mercaptoethanol into RNA and protein, can be reconstituted to infectious viral particles by stepwise dilution with cold isotonic phosphate buffered saline at pH 7.2.
Patricia Bilello, Rudolf Drzeniek
openaire +3 more sources
Summary Poliovirus, dissociated by exposure to 9 M urea and 0.09 M mercaptoethanol into RNA and protein, can be reconstituted to infectious viral particles by stepwise dilution with cold isotonic phosphate buffered saline at pH 7.2.
Patricia Bilello, Rudolf Drzeniek
openaire +3 more sources
The Morphogenesis of Poliovirus [PDF]
Poliovirus is one of the simplest and most extensively studied animal viruses. Yet, in spite of the voluminous literature, many basic and important questions concerning its morphogenesis remain unanswered. For example, what mechanisms insure that the progeny virus retain the precise structural features of the infecting particle ? How does the viral RNA
openaire +2 more sources

