Results 61 to 70 of about 20,398,982 (293)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Polish teachers’ epistemic beliefs on history as seen through the lens of social media
Historical Encounters: A Journal of Historical Consciousness, Historical Culture, and History EducationThis article is based on the content analysis of the Polish Facebook group Nauczyciele historii (“History Teachers”) which is administered by, and addressed to, practicing and prospective history teachers. The group’s over six thousand members engage and interact by writing, reading, reacting to, and commenting via as many as twenty plus posts daily ...
Joanna Wojdon, Dorota Wiśniewska
openaire +2 more sources
Studies in Polish Language and Literature
, 2022 The book offers eight case studies, covering selected problems and works from Renaissance up to the present day. Each chapter draws on a literary text(s) or problems, examining its historical context, as well as its Polish reception and presence in ...
Falkowska, Marta
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The monitoring of public opinion economic&social changes, 2016 Muzea są przestrzeniami wieloznacznymi. Z jednej strony stanowią pewne modele zbudowane na wyobrażeniach społecznych, zaś z drugiej są miejscami otwartymi na interpretacje. Są przestrzeniami relacyjnymi. Przestrzeniami rozmaitego typu relacji między innymi instytucjonalnymi, międzyludzkimi, międzynarodowymi, międzygeneracyjnymi czy międzykulturowymi ...
openaire +4 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Performance Indicators and Standards for Polish Research Libraries [PDF]
, 2003 Performance Indicators and Standards for Polish Research Libraries Abstract: The article discusses proposed standards for Polish research libraries evaluation. At the beginning, the authors present the situation of research libraries in Poland.
Widhardt, Teresa +8 more
core +1 more source
Przeszłość Demograficzna Polski, 2016 Emigration is not a new phenomenon in the Polish history. It is caused by various reasons and generates some consequences from the point of view of the state and society.
Renata Podgórzańska
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source