Results 71 to 80 of about 43,772,484 (302)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

An Attempt to Update Edward Dembowski’s Philosophy of Creation [PDF]

, 2016
The article mainly discusses Edward Dembowski's philosophy of creation in connection with his Hegelian influences, leftist associations and the ongoing discussion in nineteenth century romantic polish philosophy.
Pokorski, Bartosz Kamil
core   +1 more source

The Dirty Dozen Scale: Validation of a Polish Version and Extension of the Nomological Net

Frontiers in Psychology, 2016
In five studies (total N = 1300) we developed and validated a Polish version of the Dirty Dozen measure (DTDD-P) that measures the three traits of the Dark Triad, Machiavellianism, psychopathy, and narcissism.
A. Czarna, P. Jonason, Michael Dufner, M. Kossowska   +3 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

From the Problems of Dictionaries and Multi-lingual Corpora

Cognitive Studies | Études cognitives, 2015
From the Problems of Dictionaries and Multi-lingual Corpora The article describes the work on a number of dictionaries being developed by the Corpus Linguistics and Semantics Group of the Institute of Slavic PAS.
Violetta Koseska-Toszewa, Joanna Satoła-Staśkowiak, Wojciech Sosnowski   +2 more
doaj   +1 more source

Ukraine and Ukrainians in Perspective of Polish East- Borderland Discourse. [PDF]

, 2011
У статті обґрунтовано слушність виокремлення імагології в окрему літе- ратурознавчу дисципліну й запропоновано розглядати імагологічну пробле- матику в межах антропологічних, передовсім постколоніальних студій.
Andrusiv, Stefania, Андрусів, Стефанія   +1 more
core  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

A flexible response of NATO to potential threats occurring on the eastern border

Journal of Education, Health and Sport, 2019
From the beginning of The North Atlantic Pact has been based on the concept of collective defense. This assumption takes on meaning after 2014. The annexation of Crimea to Russia and the hybrid war in Ukraine are confirming the Increase of military ...
Robert Czerski, Marek Kustra, Krzysztof Goniewicz   +2 more
doaj  

Revealing the role of RAB27 in HER receptor family expression and signaling in melanoma cells

Cell Communication and Signaling
Background Alterations in signalling pathways fuel the growth and progression of melanoma. Therefore, understanding these processes is essential for developing effective treatment strategies.
Katarzyna Horodecka, Liliana Czernek, Łukasz Pęczek, Magdalena Klink   +3 more
doaj   +1 more source