Results 61 to 70 of about 139,634 (314)
Ultrasound‐Actuated Gene Editing in Human Kidney Organoids
Advanced Science, EarlyView.Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller +6 more
wiley +1 more source
Chinese Funding: A Curse to Africa
African Journal of Political ScienceThe role of China in the liberation of Africa from colonial rule cannot be down played as I laid a foundation to Africa today. Most African countries were aided by China militarily and ideologically in the fight against Western colonial rule.
Chido T Chipfakacha
doaj +1 more source
Explaining institutional change : why elected politicians implement direct democracy [PDF]
, 2010 Why did representative politicians introduce direct democratic reforms, thus binding their own hands? This paper presents a formal model in which (1) voters are uncertain about their representative’s preferences; (2) direct and representative ...
Hugh-Jones, David
core
Advanced Science, EarlyView.This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
The Power of the Camera-Presenting Politicians. A study in the rhetoric of camera techniques
Nordicum-Mediterraneum, 2019 The aim of this paper is to contribute to a critical phenomenological and rhetorical discussion of how politicians appear to the general public in today’s visual digital media.
Henrik Juel
doaj
Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source
Deliberative Political Leaders: The Role of Policy Input in Political Leadership
Politics and Governance, 2016 This article provides a fresh perspective on political leadership by demonstrating that government ministers take a deliberative approach to decision making.
Jennifer Lees-Marshment
doaj +1 more source
, 2022 Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
openaire +2 more sources
Money, Political Ambition, and the Career Decisions of Politicians [PDF]
In this paper we assess the impact of a variety of policies that may influence the career decisions of members of the U.S. Congress, using the empirical framework of Diermeier, Keane and Merlo (2005).
Antonio Merlo, Michael P. Keane
core
Advanced Science, EarlyView.MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou +21 more
wiley +1 more source