Results 81 to 90 of about 794,038 (307)

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

open access: yesAdvanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

They changed the history: 125 natives of the Southern Bessarabia

open access: yesЕнциклопедичний Вісник України, 2019
During the interstate scholarly project "Ukraine and Moldova: common historical memory, lessons and perspectives", the materials about the prominent personalities of science, culture and politics born in Southern Bessarabia was collected by the ...
Lilia Tsyganenko
doaj   +1 more source

Labor Supply of Politicians [PDF]

open access: yes
We examine the labor supply of politicians using data on Members of the European Parliament (MEPs). We exploit the introduction of a law that equalized MEPs' salaries, which had previously differed by as much as a factor of ten.
Emir Kamenica   +3 more
core  

Are female leaders good for education? : Evidence from India [PDF]

open access: yes, 2007
This paper shows that the gender of politicians affects the educational levels of individuals who grow up in the districts where these politicians are elected. Increasing female political representation by 10 percentage points increases the probability
Clots-Figueras, Irma
core   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Paradoxes du stigmate : les représentations médiatiques de Marine Le Pen

open access: yesGenre, Sexualité et Société, 2013
Media representations of female politicians differ from those of men involved in politics. For example, they currenly disadvantage women by linking them to the gender roles of daughter, spouse and mother, invoking skills far removed from the political ...
Frédérique Matonti
doaj   +1 more source

Top level actors speak about social policy and intergenerational inheritance of inequalities [PDF]

open access: yes, 2007
The article has been divided into two parts. In the irst one the author presents dominant trends of the contemporary academic discourse over the European social policy, in the context of progressive europeization in this ield as well and on the level ...
Woźniak, Wojciech
core  

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

open access: yesAdvanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei   +12 more
wiley   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

open access: yesAdvanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng   +8 more
wiley   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

open access: yesAdvanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth   +10 more
wiley   +1 more source

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