Results 31 to 40 of about 82,684 (300)

Governance of a complex system: water [PDF]

open access: yes, 2014
This paper sets out a complex adaptive systems view of water governance. Overview Fresh water is a life - enabling resource as well as the source of spiritual, social and economic wellbeing and development.
Elizabeth Eppel, Eppel, Elizabeth
core  

Mainstreaming Global Goals: the Impact of SGD One on Poverty Reduction in Oyo and Osun States, Nigeria

open access: yesBulletin of "Carol I" National Defense University
This study evaluates the impact of Sustainable Development Goal One (SDG 1) on poverty reduction in Nigeria, with a specific focus on Oyo and Osun States.
Abdulrauf AMBALI   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Systemic evil and the international political imagination [PDF]

open access: yes, 2016
In light of the persistence of discourses of atrocity in the post-Holocaust era, and with the resurgence of talk of evil that followed 11 September 2001, it is clear that the idea of evil still possesses a powerful hold upon the modern imagination.
Hayden, Patrick, Patrick Hayden
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Networks and Coordination in Water Politics and Governance [PDF]

open access: yes
The Handbook in which the chapter is embedded provides a global perspective on the current issues affecting water politics and governance. Focusing in particular on the policy-making process and the power dynamics that it involves, it showcases the ...
Fischer, Manuel   +3 more
core   +2 more sources

Governing Complexity in World Politics

open access: yes, 2021
Complexity is the new global ontology for world politics. This article summarizes the characteristics of complexity and its implications for informed US state policy making.
Western, Jon, Haas, Peter M
core   +1 more source

Competences That Foster Digital Transformation of Public Administrations: An Austrian Case Study

open access: yesAdministrative Sciences, 2023
Digitalisation has changed society, and, as a result, public administrations are required to undergo significant changes to satisfy emergent societal needs.
Noella Edelmann   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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