Results 241 to 250 of about 605,060 (305)

ECM‐Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling

Advanced Science, EarlyView.
Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy, Oscar André, Zhimeng Fan, Pontus Nordenfelt, Vinay S Swaminathan   +4 more
wiley   +1 more source

My grandmother's rug. [PDF]

Elife
Marder E.
europepmc   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Verifying Urdu news authenticity using deep learning with concatenated BERT and GloVe embedding. [PDF]

Sci Rep
Feroz A, Abbasi W, Babar MZ, Aljohani A.
europepmc   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

The narration of status in far-right populist foreign policy: the United States of Trump 2.0. [PDF]

J Int Relat Dev (Ljubl)
Wehner LE.
europepmc   +1 more source

A fuzzy-microeconomics model for priority-based content centric routing in internet of things. [PDF]

Sci Rep
Xu J, Chen Q.
europepmc   +1 more source

A Lightweight Hybrid Detection System Based on the OpenMV Vision Module for an Embedded Transportation Vehicle. [PDF]

Sensors (Basel)
Wang X, Gao H, Ma X, Wang L.
europepmc   +1 more source

Neuropsychology and Politics Collide in the 2024 US Presidential Election: Pitfalls of attacks on age, language, and memory. [PDF]

J Neuropsychol
Reilly J.
europepmc   +1 more source