Results 71 to 80 of about 127,000 (225)
Allergy, EarlyView.High‐dose birch‐extract nasal challenge induced synchronous peaks at 4 weeks in serum specific IgE (sIgE) and basophil sensitivity. Mast cell sensitivity via tSPT and sIgG1 and sIgG4 responses peaked later, at 6–8 weeks. Preseasonal allergen exposure attenuated seasonal sIgE increase and prevented further rise in tSPT sensitivity.
N. J. Campion +18 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche +11 more
wiley +1 more source
Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions
Allergy, EarlyView.Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira +13 more
wiley +1 more source
Allergy, EarlyView.Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang +12 more
wiley +1 more source
CaryologiaHomologous recombination promotes genetic diversity by exchanging genetic material between homologs, ensuring unique combinations of alleles in offspring.
Sunita Arora, Monika Vyas, Meena Barupal
doaj +1 more source
Seasonal variation of apparent male fertility and 2n pollen production in plantain and banana
, 2018 Current efforts to produce improved genotypes of plantain (Musa spp. AAB genomic group) and banana (Musa spp. AAA genomic group) depend on identifying triploid, female-fertile clones and crossing them with male-fertile, diploid wild or cultivated ...
Okoro, J., Ortíz, R., Ulburghs, F.
core +1 more source
, 2022 Data for publication at MDPI Insects. Sorted according to Figures in the publication. Fig2: Bright field images of Hypochaeris radicata pollen on glass before and after each of several centrifugation experiments.
Steven Huth (13005360)
core +1 more source
Allergy, EarlyView.This study examined whether antibiotic use altered the risk of infant allergic disease within a maternal prebiotics supplementation trial. Intrapartum antibiotics were maternal antibiotics administered during childbirth, from the onset of labour or induction until 1‐h before delivery.
Summer V. M. Walker +10 more
wiley +1 more source
Reconsidering amateur photography:an introduction
, 2012 As an introduction to the Reconsidering Amateur Photography strand of the National Media Museum's EitherAnd website, this conversation between Annebella Pollen and Juliet Baillie frames the core theories, debates and challenges in the area of ...
Baillie, Juliet +1 more
core
Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy
Allergy, EarlyView.We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov +43 more
wiley +1 more source