Results 181 to 190 of about 41,870 (312)

High Fatigue‐Resistant Photoswitches Based on iridium(III)‐DTE Systems

open access: yesChemistry – A European Journal, EarlyView.
Coordination to iridium(III) enhances fatigue resistance over multiple photoswitching cycles in diarylethenes. This metal coordination modulates photoresponse relative to the free ligands under identical irradiation conditions, opening new avenues for practical applications.'' ABSTRACT A series of four differently substituted nonsymmetrical ...
Ariadna Pazos   +6 more
wiley   +1 more source

Public involvement in the design of a complex neurosurgical clinical trial (the GDNF trial) and an associated support package: reflections and recommendations. [PDF]

open access: yesTrials
Bakshi N   +13 more
europepmc   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

open access: yesCytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook   +2 more
wiley   +1 more source

Engineering and Characterization of a Fluorescent Fission Yeast Arp2/3 Complex for Single Molecule Mechanistic Investigations

open access: yesCytoskeleton, EarlyView.
ABSTRACT Arp2/3 complex is a seven‐component protein complex that facilitates the assembly of branched actin filament networks by binding to pre‐existing “mother” actin filaments and initiating the nucleation of new branched “daughter” filaments. Arp2/3 complex must be activated by a nucleation promoting factor such as the WASP/Scar protein family. The
Caitlin A. Anderson   +8 more
wiley   +1 more source

Cytoskeleton–Membrane Uncoupling in Duchenne Muscular Dystrophy: Implications for Newborn Screening and Early Protection

open access: yesCytoskeleton, EarlyView.
ABSTRACT The cytoskeleton of striated muscle integrates force transmission, mechanotransduction, and sarcolemmal stability through coordinated networks of sarcomeres, costameres, and intermediate filaments. Together, these systems establish mechanical continuity between the contractile apparatus, the sarcolemma, and the extracellular matrix.
Houda Cohen   +3 more
wiley   +1 more source

Acceptability of digitally adapted cardiovascular risk reduction intervention content from the StrongPeople strong hearts program: A single-arm pilot study. [PDF]

open access: yesDigit Health
On A   +7 more
europepmc   +1 more source

Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Human gestation is characterized by dynamic changes in maternal physiology and maturation of tissue functions before and after birth. The fetus and neonate are highly dependent upon transfer of maternal nutrients via the placenta and lactating mammary gland, which frequently involve selective membrane transporter proteins.
Joanne Wang   +16 more
wiley   +1 more source

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