Results 291 to 300 of about 487,952 (342)

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Air pollution exposure and multimorbidity patterns: evidence from a national cohort study in China. [PDF]

BMC Public Health
Cao Y, Hao J, Quan M, Ge C, Li X, Wang J, Chen F, Wang D, Pei L, Kang Y.   +9 more
europepmc   +1 more source

The Impact of Persistent Organic Pollutants on Neural Development Using an In Vitro Approach

, 2018
Nichlas Davidsen
openalex   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source

Investigation of road transport-based greenhouse gas prediction models and the use of ıntelligent transportation systems for emission reduction. [PDF]

Sci Rep
Beba H, Öztürk Z.
europepmc   +1 more source

Chemical advances in transforming pollutants into new materials

Tales S. Daitx
openalex   +2 more sources

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Air Pollution Exposure and Muscle Mass and Strength Decline in Older Adults: Results From a Swedish Population-Based Study. [PDF]

J Cachexia Sarcopenia Muscle
Trevisan C, Gregorio C, Welmer AK, Volpato S, Eneroth K, Bellander T, Vetrano DL, Rizzuto D.   +7 more
europepmc   +1 more source

Daytime pollutant accumulation driven by suppressed near-surface mixing in dense high-rise building canopies

Jong-Won Kim, Sang‐Woo Kim
openalex   +1 more source

Trapped in the Greenhouse?: Regulating Carbon Dioxide after FDA v. Brown & Williamson Tobacco Corp. [PDF]

, 2004
Baird, J. Christopher
core   +1 more source