Results 341 to 350 of about 3,561,143 (397)

A phase I evaluation of poly(I,C)-LC in cancer patients.

Journal of biological response modifiers, 1986
Twenty-five patients with metastatic carcinoma were entered into a Phase I clinical trial using poly(I,C)-LC at either 1 mg/m2 or 4 mg/m2 intravenous, twice weekly, for 4 weeks. None of the 15 patients entered at the 1 mg/m2 dose had an objective response; three had progressive disease.
H C, Stevenson, P G, Abrams, C S, Schoenberger, R B, Smalley, R B, Herberman, K A, Foon   +5 more
openaire   +1 more source

Pharmacokinetic and therapeutic activity of polyinosinic-polycytidylic acid stabilized with poly-L-lysine in carboxymethylcellulose [poly(I,C)-LC].

Journal of biological response modifiers, 1986
Polyinosinic-polycytidylic acid stabilized with poly-L-lysine in carboxymethylcellulose [poly(I,C)-LC] significantly augmented natural killer (NK) cell activity in several tissues. Macrophage (M phi) tumoricidal activity was also markedly increased. Both effector cells were active for 9 days. Poly(I,C)-LC also increased effector cell response in vitro.
M A, Chirigos, E, Schlick, R, Ruffmann, W, Budzynski, P, Sinibaldi, E, Gruys   +5 more
openaire   +1 more source

Photochemical Cross-Linking of Poly(ethylene terephthalate-co-2,6-anthracenedicarboxylate)

Macromolecules, 2000
Poly(ethylene terephthalate) copolymers containing 2,6-anthracenedicarboxylate structural units are chain extended and cross-linked by irradiation at 350 nm. The cross-linked materials were characterized by NMR, UV−vis, DSC, and dilute solution viscometry.
Jeffrey R. Jones, Charles L. Liotta, David M. Collard, David A. Schiraldi   +3 more
openaire   +1 more source

Structure, Mobility, and Domain Sizes in Poly(chloromethylsilane-co-styrene)

Macromolecules, 2000
The structure of poly(chloromethylsilane-co-styrene) obtained from styrene and chloromethyldisilanes is investigated by HR liquid and solid-state NMR techniques. 1H−13C DEPT and 1H−29Si HMBC investigations indicate that the system has to be considered as a polymer blend consisting of poly(chloromethylsilane) and polystyrene. Differences in the mobility
E. Brendler, Ch. Jäger, D. Scheller, G. Roewer   +3 more
openaire   +1 more source

The synthesis and characterization of poly d(I-C) poly d(I-C)

Journal of the American Chemical Society, 1968
R C, Grant, S J, Harwood, R D, Wells
openaire   +2 more sources

Relationship of biological activities of poly I-poly C to homopolymer molecular weights.

Nature: New biology, 1971
J. Niblack, M. McCreary
semanticscholar   +1 more source

Sepharose-bound poly (I)-poly (C): interaction with cells and interferon production.

Biochemical and Biophysical Research Communications - BBRC, 1975
L. Bachner, E. De Clercq, M. Thang
semanticscholar   +1 more source

Mode of Action of the Anti-AIDS Compound Poly(I)·Poly(C12U) (Ampligen): Activator of 2′,5′-Oligoadenylate Synthetase and Double-Stranded RNA-Dependent Kinase

Journal of Interferon Research, 1993
Hiroshi Ushijima, Peter G. Rytik, Heike Schäcke, Ute Scheffer, Werner E.G. Müller, H. Schröder   +5 more
semanticscholar   +1 more source

Adjuvant effects on poly I poly C in New Zealand mice.

Arthritis & Rheumatism, 1972
M. E. Jacobs, A. Steinberg, J. Gordon, N. Talal   +3 more
semanticscholar   +1 more source

In vitro stimulation of spleen cell cultures by poly I: poly C and levamisole.

Cellular Immunology, 1974
W. Woods, M. Siegel, M. Chirigos
semanticscholar   +1 more source