Results 91 to 100 of about 9,399 (192)

Multi‐Responsive PAA/PNIPAM Semi‐IPN Hydrogel Properties Controlled by PAA Topology

open access: yesMacromolecular Rapid Communications, Volume 47, Issue 15, 4 August 2026.
Polymer topology governs hydrogel behavior in semi‐interpenetrating networks. Cyclic poly(acrylic acid) enables controlled pH‐responsive swelling, improved stability, and enhanced deformability compared to linear analogues, while linear systems show higher strength during thermal de‐swelling.
Suraj Aswale   +7 more
wiley   +1 more source

3D Liver Fibrosis Models in Lab: A Novel Modality for Drug Screening

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Liver fibrosis is the common consequence of liver injury caused by a variety of chronic liver disorders. This condition leads to the development of more severe complications, particularly cirrhosis and hepatocellular carcinoma. Despite abundant studies, the fundamental cell and molecular mechanisms of liver fibrosis are still unknown.
Hani Keshavarz Alikhani   +10 more
wiley   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

open access: yesSmall Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu   +3 more
wiley   +1 more source

Characterization of complexation of poly (N-isopropylacrylamide-co-2-(dimethylamino) ethyl methacrylate) thermoresponsive cationic nanogels with salmon sperm DNA

open access: yesInternational Journal of Nanomedicine, 2009
Jim Moselhy1, Tasnim Vira1, Fei-Fei Liu2, Xiao Yu Wu11Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada; 2Ontario Cancer Institute, Toronto, ON, CanadaAbstract: Thermoresponsive cationic ...
Jim Moselhy   +3 more
doaj  

Fabrication of switchable biocompatible, nano-fluidic devices using a thermoresponsive polymer on nano-patterned surfaces

open access: yesMicro and Nano Engineering
In this study, a method for depositing and patterning the thermosensitive polymer poly(N-isopropylacrylamide) on SiO2 surfaces is presented for potential use in nano-sized microfluidic channels.
Ch. Bickmann   +7 more
doaj   +1 more source

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