Results 131 to 140 of about 27,905 (245)

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

open access: yesSmall, EarlyView.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito   +2 more
wiley   +1 more source

A Microfluidic Gradient Generator Post‐Modified by Two‐Photon Direct Laser Writing for Dynamic Particle Functionalization

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 21, June 5, 2026.
We present a Christmas‐tree‐shaped microfluidic gradient generator (MGG) that is equipped with dynamic trapping chambers, based on thermoresponsive microactuators. At room temperature, amine‐functionalized polystyrene beads are trapped inside the pNIPAM funnels and fluorescently labeled.
Chantal Barwig   +6 more
wiley   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu   +9 more
wiley   +1 more source

Freeze‐Derived Microporous Biomaterials for Tissue Engineering Applications

open access: yesSmart Medicine, Volume 5, Issue 3, June 2026.
Ice‐templating demonstrates significant potential to revolutionize tissue engineering through freeze‐induced microphase separation for fabricating hierarchical, biomimetic scaffolds. This review comprehensively examines recent advances in mechanisms and applications in tissue engineering, such as 3D cell culture, wound healing, bone regeneration, nerve
Shuangshuang Miao   +6 more
wiley   +1 more source

Characterization of complexation of poly (N-isopropylacrylamide-co-2-(dimethylamino) ethyl methacrylate) thermoresponsive cationic nanogels with salmon sperm DNA

open access: yesInternational Journal of Nanomedicine, 2009
Jim Moselhy1, Tasnim Vira1, Fei-Fei Liu2, Xiao Yu Wu11Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada; 2Ontario Cancer Institute, Toronto, ON, CanadaAbstract: Thermoresponsive cationic ...
Jim Moselhy   +3 more
doaj  

Fabrication of switchable biocompatible, nano-fluidic devices using a thermoresponsive polymer on nano-patterned surfaces

open access: yesMicro and Nano Engineering
In this study, a method for depositing and patterning the thermosensitive polymer poly(N-isopropylacrylamide) on SiO2 surfaces is presented for potential use in nano-sized microfluidic channels.
Ch. Bickmann   +7 more
doaj   +1 more source

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