Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito +2 more
wiley +1 more source
We present a Christmas‐tree‐shaped microfluidic gradient generator (MGG) that is equipped with dynamic trapping chambers, based on thermoresponsive microactuators. At room temperature, amine‐functionalized polystyrene beads are trapped inside the pNIPAM funnels and fluorescently labeled.
Chantal Barwig +6 more
wiley +1 more source
Dual pH- and Thermo-Sensitive Poly(N-isopropylacrylamide-co-allylamine) Nanogels for Curcumin Delivery: Swelling-Deswelling Behavior and Phase Transition Mechanism. [PDF]
Santhamoorthy M, Kim SC.
europepmc +1 more source
Innovative Drug Delivery Systems for the Treatment of Glaucoma
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu +9 more
wiley +1 more source
Conductive and Thermo-Responsive Composite Hydrogels with Poly(N-isopropylacrylamide) and Carbon Nanotubes Fabricated by Two-Step Photopolymerization. [PDF]
Ciarleglio G, Toto E, Santonicola MG.
europepmc +1 more source
Freeze‐Derived Microporous Biomaterials for Tissue Engineering Applications
Ice‐templating demonstrates significant potential to revolutionize tissue engineering through freeze‐induced microphase separation for fabricating hierarchical, biomimetic scaffolds. This review comprehensively examines recent advances in mechanisms and applications in tissue engineering, such as 3D cell culture, wound healing, bone regeneration, nerve
Shuangshuang Miao +6 more
wiley +1 more source
Jim Moselhy1, Tasnim Vira1, Fei-Fei Liu2, Xiao Yu Wu11Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada; 2Ontario Cancer Institute, Toronto, ON, CanadaAbstract: Thermoresponsive cationic ...
Jim Moselhy +3 more
doaj
Utilization of CO2 in supercritical conditions for the synthesis of cyclic poly (N-isopropylacrylamide) via emulsion and homogeneous reactions. [PDF]
Daneshyan S, Sodeifian G.
europepmc +1 more source
In this study, a method for depositing and patterning the thermosensitive polymer poly(N-isopropylacrylamide) on SiO2 surfaces is presented for potential use in nano-sized microfluidic channels.
Ch. Bickmann +7 more
doaj +1 more source
Highly Sensitive Poly-N-isopropylacrylamide Microgel-based Electrochemical Biosensor for the Detection of SARS-COV-2 Spike Protein. [PDF]
Chen H +7 more
europepmc +1 more source

