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Poly(N-isopropylacrylamide) branched polymer nanoparticles

Polymer Chemistry, 2011
A series of thermally responsive branched copolymers based on N-isopropylacrylamide (NIPAAm) and poly(ethylene glycol) methacrylate (PEGMA) are synthesized using a direct, single step modified free radical polymerization strategy. The aqueous solution behaviour and nanoparticle formation of these copolymers are studied and correlated to the NIPAAm ...
Pierre Chambon   +5 more
openaire   +1 more source

Micellization and phase transition behavior of thermosensitive poly(N-isopropylacrylamide)–poly(ɛ-caprolactone)–poly(N-isopropylacrylamide) triblock copolymers

Polymer, 2008
Abstract Thermosensitive triblock copolymers with two hydrophilic poly( N -isopropylacrylamide) blocks flanking a central hydrophobic poly(ɛ-caprolactone) block were synthesized by atom transfer radical polymerization. Core-shell micellization of the triblock copolymers was inferred from the 1 H NMR spectra derived in two different solvent ...
Loh, X.J.   +8 more
openaire   +1 more source

Cytocompatible Performance of Thermosensitive Poly(N-Isopropylacrylamide) Nanoparticles

Journal of Biomaterials Science, Polymer Edition, 2012
The development of biomedical materials with biocompatibility, especially cytocompatibility, is the frontal research field for material science, biology, medicine, pharmacology and related interdisciplines. We have successfully synthesized a new biomedical material, PNIPAM-g-P(NIPAMco-St) (PNNS) core-shell nanoparticles, and investigated its ...
Guo-Hui, Zhang   +4 more
openaire   +2 more sources

Glucose sensitive poly (N-isopropylacrylamide) microgel based etalons

Analytical and Bioanalytical Chemistry, 2012
Thermoresponsive microgels have been shown to be an excellent platform for designing sensor materials. Recently, poly (N-isopropylacrylamide)-co-acrylic acid (pNIPAm-co-AAc) microgel based etalon materials have been described as direct sensing materials that can be designed to have a single, unique color.
Courtney D, Sorrell, Michael J, Serpe
openaire   +2 more sources

Properties of Poly(N-isopropylacrylamide)-Grafted Colloidal Silica

Journal of Colloid and Interface Science, 2000
Poly(N-isopropylacrylamide-co-3-trimethoxysilylpropyl methacrylate) was prepared by radical polymerization and was grafted onto the surface of spherical colloidal silica. The copolymer, which had on average 1 silyl group per chain, condensed on the silica dispersed in THF at 60 degrees C. The resulting particles had a critical coagulation concentration
, Liu, , Pelton, , Hrymak
openaire   +2 more sources

Poly(N-isopropylacrylamide) (PNIPAM) is never hydrophobic

Journal of Colloid and Interface Science, 2010
PNIPAM chains have hydrophobic and hydrophilic domains below and above the LCST. Temperature dependent interactions between PNIPAM and solutes arise because of changes in the local environment around the hydrophobic isopropyl domains. Below the LCST the isopropyl groups are surrounded by water, whereas above the LCST the hydrophobic groups are in ...
openaire   +2 more sources

Solution Properties of Poly(N-isopropylacrylamide)

Journal of Macromolecular Science: Part A - Chemistry, 1968
Abstract Aqueous solutions of poly(N-isopropyl acrylamide) show a lower critical solution temperature. The thermodynamic properties of the system have been evaluated from the phase diagram and the heat absorbed during phase separation and the phenomenon is ascribed to be primarily due to an entropy effect.
M. Heskins, J. E. Guillet
openaire   +1 more source

The viscosity of dilute poly(N-isopropylacrylamide) dispersions

Journal of Colloid and Interface Science, 2011
The viscosity of dilute aqueous dispersions of poly(N-isopropylacrylamide) microgel particles is measured by capillary viscometry. The viscosity increases with particle mass fraction and on reducing temperature, particularly below the volume phase transition temperature (VPTT) of 32 °C.
Anya J, Howe   +2 more
openaire   +2 more sources

The effect of pH on the LCST of poly(N-isopropylacrylamide) and poly(N-isopropylacrylamide-co-acrylic acid)

Journal of Biomaterials Science, Polymer Edition, 2004
Poly(N-isopropylacrylamide) (PNIPAAm) and poly(N-isopropylacrylamide-co-acrylic acid) (P(NIPAAm-co-AAc)) hydrogels are synthesized by irradiating the aqueous solutions of NIPAAm and NIPAAm/AAc with 60Co gamma-ray. The effects of pH on the swelling ratio and on the lower critical solution temperature (LCST) are studied by determining the dependence of ...
Yong, Pei   +6 more
openaire   +2 more sources

Cytotoxic evaluation of N-isopropylacrylamide monomers and temperature-sensitive poly(N-isopropylacrylamide) nanoparticles

Journal of Nanoparticle Research, 2008
The objective of this research project is to investigate the biocompatibility of N-isopropylacrylamide (NIPAAm) monomers and poly(N-isopropylacrylamide) (PNIPAAm) nanoparticles in vitro. PNIPAAm nanoparticles of different sizes were synthesized and characterized by transmission electron microscopy and dynamic light scattering.
Aniket S. Wadajkar   +3 more
openaire   +1 more source

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