Advanced Science, EarlyView.Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin +10 more
wiley +1 more source
Molecular Structure Regulation of Polyacrylamide-Based Drag Reducers on Solubility and Transient Gel-Layer Behavior: Molecular Dynamics and Experimental Study. [PDF]
GelsXu K +8 more
europepmc +1 more source
Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy
Advanced Science, EarlyView.A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan +9 more
wiley +1 more source
UV-Synthesized Polyacrylamide-Based Polymer Sensor for Measuring Soil-Water Characteristic Curves in Unsaturated Soils. [PDF]
Polymers (Basel)Arinova A +6 more
europepmc +1 more source
Advanced Science, EarlyView.Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi +7 more
wiley +1 more source
Novel Superabsorbent Hydrogels Based on Polyacrylamide and White Angico Gum Enhanced with Kaolinitic Clay and Soapstone for Potential Agricultural Applications. [PDF]
Int J Mol SciCarvalho AS +5 more
europepmc +1 more source
Advanced Science, EarlyView.A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv +16 more
wiley +1 more source
Rheology and Oil-Water Emulsion Stability During Biodegradation of Hydrolyzed Polyacrylamide by <i>Delftia lacustris</i> EPDB-8. [PDF]
Polymers (Basel)Sun B +8 more
europepmc +1 more source
Advanced Science, EarlyView.This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan +7 more
wiley +1 more source
From biopolymer to archaeological protector: glycogen-<i>g</i>-polyacrylamide as a nano-consolidant for the reinforcement of fragile parchment manuscripts. [PDF]
RSC AdvAbdel-Maksoud G, Hashem MS.
europepmc +1 more source