Results 71 to 80 of about 53,957 (281)

Coronary Artery Ectasia in a Patient with Polycystic Kidney Disease

Journal of Cardiovascular and Thoracic Research, 2011
A 44 years old male patient with acute coronary syndrome and polycystic kidney disease is described. Coronary angiography showed ectatic coronary arteries.
Leili Pourafkari, Samad Ghaffari, Bizhan Zamani, Mehdi Tolui   +3 more
doaj   +1 more source

An Unusual Cardiac Manifestation in Autosomal Dominant Polycystic Kidney Disease

Case Reports in Nephrology, 2012
Autosomal dominant polycystic kidney disease is a common hereditary disorder characterized by renal and extrarenal, cystic and noncystic manifestations. Connective tissue defects, including cerebral aneurysm, meningeal diverticula, abdominal wall hernias,
Fausta Catapano, Stefano Pancaldi, Carlo Pace Napoleone, Lucia Barbara De Sanctis, Gaetano Gargiulo, Giuseppe Emiliani, Antonio Santoro   +6 more
doaj   +1 more source

New Therapies Targeting Cystogenesis in Autosomal Polycystic Kidney Disease [PDF]

, 2017
Autosomal dominant polycystic kidney disease is the most common inherited kidney disease and results from mutations in the polycystin 1 gene (PKD1) or the polycystin 2 gene (PKD2).
Aris Tsalouchos, Maurizio Salvadori
core  

Heat-shock mediated overexpression of HNF1β mutations has differential effects on gene expression in the Xenopus pronephric kidney. [PDF]

, 2012
The transcription factor HNF1B, encoded by the TCF2 gene, plays an important role in the organogenesis of vertebrates. In humans, heterozygous mutations of HNF1B are associated with several diseases, such as pancreatic β-cell dysfunction leading to ...
Sauert, Kathrin, Gull, Mazhar, André W Brändli, Christoph Waldner, Brändli, André W., Mazhar Gull, Roose, Magdalena, Gerhart U. Ryffel (177327), Kathrin Sauert (177290), Kahnert, Stefan, Ryffel, Gerhart U., Waldner, Christoph, Kathrin Sauert, Magdalena Roose, Magdalena Roose (177306), Stefan Kahnert (177298), Gerhart U Ryffel, André W. Brändli (177322), Stefan Kahnert, Christoph Waldner (177333), Mazhar Gull (177314)   +20 more
core   +1 more source

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

Perioperative Management of Hysterectomy in a Patient with Polycystic Kidney Disease [PDF]

Journal of Clinical and Diagnostic Research, 2014
Polycystic disease of the kidney, inherited as an autosomal dominant trait is characterised by progressive expansion of numerous fluidfilled cysts resulting in massive enlargement of the kidneys ultimately resulting in kidney failure. An understanding of
Savitri. K., Ashwini. H.R., Sreedevi. S.
doaj   +1 more source

Emerging key roles for P2X receptors in the kidney [PDF]

, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides.
Peppiatt-Wildman, Claire M., Peppiatt-Wildman, C. M., Wildman, S. S., R. E. Birch, C. M. Peppiatt-Wildman, Scott S Wildman, Schwiebert, E. M., Wildman, Scott S.P., E. M. Schwiebert, S. S. Wildman, Birch, R. E.   +10 more
core   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Renal ultrasound after first febrile urinary tract infection in hospitalized children: The ROUTINE prospective observational study protocol

Journal of Hospital Medicine, EarlyView.
Abstract Background Urinary tract infection (UTI) is a common reason for hospitalization in young children. American and Canadian guidelines recommend universal renal ultrasound after a first febrile UTI to identify genitourinary abnormalities that require further management, despite limited supporting evidence. The Renal ultrasOund after first febrile
Sanjay Mahant, Keenjal Mistry, Ann Bayliss, Nicholas Barrowman, Karen Born, Cornelia Borkhoff, Raman Chawla, David D'Arienzo, Aurelie D'Hondt, Kim De Castris‐Garcia, Joana Dos Santos, Olivier Drouin, Ricardo Faingold, Vince Albert Flores, Jessica Foulds, Jeremy Friedman, Lucy Giglia, Joanna Holland, Radha Jetty, Kristopher Kang, Patricia Li, Grace Leo, Armando Lorenzo, Elise Lu, Colin Macarthur, Kyle Millar, Myla E. Moretti, Nassr Nama, Olivia Ostrow, Rachel Pearl, Patricia Parkin, Mandy Rickard, Mahmoud Sakran, Anupam Sehgal, Nader Shaikh, Sepideh Taheri, Otto G. Vanderkooi, Gemma Vomiero, Kim Zhou, Peter J. Gill, the Canadian Paediatric Inpatient Research Network (PIRN)   +40 more
wiley   +1 more source

Grayscale ultrasound characteristics of autosomal dominant polycystic kidney disease severity – an adult and pediatric cohort study

, 2017
Introduction: The most common hereditary kidney condition is autosomal dominant polycystic kidney disease. It is the cause of 5–10% of end-stage renal disease.
Marcin Tkaczyk, Podgórski, Michał, Michał Podgórski, Tkaczyk, Marcin, Marcin Strzelczyk, Afshari, Susan, Pawlak-Bratkowska, Monika, Strzelczyk, Marcin, Piotr Grzelak, Grzelak, Piotr, Susan Afshari, Monika Pawlak-Bratkowska   +11 more
core   +1 more source