Polycystic Liver Disease: Pathophysiology, Diagnosis and Treatment [PDF]
Hepatic Medicine: Evidence and Research, 2022 Luiz Fernando Norcia,1 Erika Mayumi Watanabe,2 Pedro Tadao Hamamoto Filho,3 Claudia Nishida Hasimoto,1 Leonardo Pelafsky,1 Walmar Kerche de Oliveira,1 Ligia Yukie Sassaki4 1Department of Surgery, São Paulo State University (Unesp), Medical School ...
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A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease. [PDF]
Sci Transl Med, 2023 The formation of multiple cysts in the liver occurs in a number of isolated monogenic diseases or multisystemic syndromes, during which bile ducts develop into fluid-filled biliary cysts.
Waddell SH +17 more
europepmc +2 more sources
Simultaneous Echinococcal superinfection in a patient with polycystic liver disease [PDF]
Clinical Case Reports, 2023 Key Clinical Message Concurrent polycystic liver disease and echinococcus infection can hinder diagnosis. Surgery may be needed for accurate diagnosis and treatment. Multidisciplinary collaboration is crucial.
Ottavia Cicerone +3 more
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Polycystic Liver Disease: Advances in Understanding and Treatment. [PDF]
Annu Rev Pathol, 2022 Polycystic liver disease (PLD) is a group of genetic disorders characterized by progressive development of cholangiocyte-derived fluid-filled hepatic cysts.
Masyuk TV, Masyuk AI, LaRusso NF.
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An Empirical Biomarker-based Calculator for Autosomal Recessive Polycystic Kidney Disease - The Nieto-Narayan Formula [PDF]
, 2016 Autosomal polycystic kidney disease (ARPKD) is associated with progressive enlargement of the kidneys fuelled by the formation and expansion of fluid-filled cysts. The disease is congenital and children that do not succumb to it during the neonatal period will, by age 10 years, more often than not, require nephrectomy+renal replacement therapy for ...
Goldberg, Itzhak D. +3 more
arxiv +13 more sources
Estrogens in polycystic liver disease: A target for future therapies? [PDF]
Liver Int, 2021 Patients suffering from polycystic liver disease (PLD) can develop large liver volumes, leading to physical and psychological complaints, reducing quality of life. There is an unmet need for new therapies in these patients.
Aapkes SE +5 more
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Abdominal wall hernia is a frequent complication of polycystic liver disease and associated with hepatomegaly. [PDF]
Liver Int, 2022 Polycystic liver disease (PLD) is related to hepatomegaly which causes an increased mechanical pressure on the abdominal wall. This may lead to abdominal wall herniation (AWH). We set out to establish the prevalence of AWH in PLD and explore risk factors.
Barten TRM +5 more
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Polycystic liver disease presenting with an exudative pleural effusion: a case report [PDF]
Journal of Medical Case Reports, 2012 Introduction Polycystic liver disease is asymptomatic in 95% of patients. In the remaining 5% it causes symptoms due to the local mass effect of the polycystic liver. We describe the case of a patient who presented with symptoms of a pleural effusion and
Woolnough Kerry +2 more
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Rationale and design of the RESOLVE trial: lanreotide as a volume reducing treatment for polycystic livers in patients with autosomal dominant polycystic kidney disease [PDF]
BMC Nephrology, 2012 Background A large proportion of patients with autosomal dominant polycystic kidney disease (ADPKD) suffers from polycystic liver disease. Symptoms arise when liver volume increases.
Gevers Tom JG +3 more
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Liver transplantation in adult polycystic liver disease: the Ontario experience. [PDF]
BMC Gastroenterol, 2021 Background Liver transplantation (LT) remains the curative treatment for symptomatic Polycystic Liver Disease (PCLD) patients and is associated with excellent survival rates.
Alsager M +12 more
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