Results 161 to 170 of about 5,508,271 (271)

Novel α-1,3-Glucosyltransferase Variants and Their Broad Clinical Polycystic Liver Disease Spectrum. [PDF]

Genes (Basel), 2023
Boerrigter MM, Te Morsche RHM, Venselaar H, Pastoors N, Geerts AM, Hoorens A, Drenth JPH.   +6 more
europepmc   +1 more source

Subclinical cardiac alterations and cardiometabolic profile in adolescents with newly diagnosed polycystic ovary syndrome: A cross‐sectional comparative echocardiographic study

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 310-321, October 2026.
Abstract Objective While cardiometabolic comorbidities have been well established in adults with polycystic ovary syndrome (PCOS), it remains unclear whether the early signs of cardiovascular morbidity emerge during adolescence. This study aimed to investigate whether metabolic and cardiovascular alterations begin in adolescents with PCOS.
Demet Aygün Ari, Melis Pehlivantürk Kizilkan, Musa Öztürk, İlker Ertuğrul, Hayrettin Hakan Aykan, Tevfik Karagöz, Nuray Kanbur, Orhan Derman, Sinem Akgül   +8 more
wiley   +1 more source

Polycystic kidney disease: inheritance, pathophysiology, prognosis, and treatment

, 2010
Christian R Halvorson1, Matthew S Bremmer1, Stephen C Jacobs11Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USAAbstract: Both autosomal dominant and recessive polycystic kidney disease are conditions with severe ...
Stephen C Jacobs, Matthew S Bremmer, Christian R Halvorson   +2 more
core  

The population frequency of predicted pathogenic variants in the genes associated with Autosomal Dominant Polycystic Liver Disease (ADPLD) and kidney cysts. [PDF]

PLoS One
Varughese S, Huang M, Savige J.
europepmc   +1 more source

A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease. [PDF]

Sci Transl Med, 2023
Waddell SH, Yao Y, Olaizola P, Walker A, Jarman EJ, Gournopanos K, Gradinaru A, Christodoulou E, Gautier P, Boerrigter MM, Cadamuro M, Fabris L, Drenth JP, Kendall TJ, Banales JM, Khamseh A, Mill P, Boulter L.   +17 more
europepmc   +1 more source

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 396-407, October 2026.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

Limitations of MELD in Isolated Polycystic Liver Disease: Fatal Traumatic Cyst Rupture Complicated by Abdominal Compartment Syndrome. [PDF]

Case Reports Hepatol
Vinton ZC, Schulz CA, Melquist SJ, Kulig CC.   +3 more
europepmc   +1 more source

Evidence of nonsurgical treatment for polycystic liver disease. [PDF]

Ther Adv Chronic Dis, 2022
Yoo JJ, Jo HI, Jung EA, Lee JS, Kim SG, Kim YS, Kim BK.   +6 more
europepmc   +1 more source

SIRT3‐Dependent Actions of Berberine: From Molecular Therapies to Toxicity

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
This study reveals that berberine's therapeutic versatility in metabolic, cardiovascular, and hepatic disorders stems from its modulation of the mitochondrial protein Sirt3. Understanding this mechanism explains both its broad efficacy and its organ‐specific toxicity, positioning berberine as a promising mitochondrial epigenetic modulator whose ...
Dareuosh Shackebaei, Seyed Shahram Miraghaee, Faegheh Farhadi, Abolfazl Akbarzadeh, Fatemeh Yarmohammadi   +4 more
wiley   +1 more source

Scoping Review on Polycystic Liver Disease in PKD1/PKD2 Gene Carriers: Genetic Aspects, Pathophysiology, and Therapeutic Approaches. [PDF]

J Clin Exp Hepatol
Muñoz-Delgado DY, Zuñiga-Hernández LF, Barrios-Bermúdez H, Velasco-Erira S, Diaz-Brochero C, Suarez-Quintero CY.   +5 more
europepmc   +1 more source