Results 61 to 70 of about 50,700 (248)
A systems-biology approach to understanding the ciliopathy disorders. [PDF]
'Ciliopathies' are an emerging class of genetic multisystemic human disorders that are caused by a multitude of largely unrelated genes that affect ciliary structure/function.
Gleeson, Joseph G, Lee, Ji Eun
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Letrozole treatment of pubertal female mice results in activational effects on reproduction, metabolism and the gut microbiome. [PDF]
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged women that is comprised of two out of the following three features: hyperandrogenism, oligo- or amenorrhea, or polycystic ovaries. In addition to infertility, many women
Arroyo, Pablo+4 more
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A 33 year old primagravida rhesus positive woman was referred to the Emergency Department by her family doctor at 27 weeks gestation. At 25 weeks of gestation, she had been diagnosed with hypertension and was started on labetalol therapy.
Bugeja, Roberta, Galdes, Caroline
core
Phosphoprotein enriched in astrocytes (PEA)-15 : A potential therapeutic target in multiple disease states [PDF]
Copyright © 2014 Elsevier Inc.
Greig, Fiona H, Nixon, Graeme F
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Polycystic liver and kidney diseases
There have been remarkable advances in research on polycystic liver and kidney diseases recently, covering cloning of new genes, refining disease classifications, and advances in understanding more about the molecular pathology of these diseases. Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disease affecting ...
Esa Tahvanainen+3 more
openaire +3 more sources
Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. [PDF]
Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disease that leads to renal failure in the majority of patients. The very first pharmacological treatment, tolvaptan, received Food and Drug Administration approval in 2018 ...
Bourgeois, Bryan C+4 more
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Complications of Cushing's syndrome: state of the art [PDF]
Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and excessive secretion of cortisol. The syndrome is associated with increased mortality and impaired quality of life because of the occurrence of comorbidities.
Biller, Beverly M. K+5 more
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A 65-year-old man was referred to the Gastroenterology Department with complaints of longstanding upper abdominal discomfort and hepatomegaly. Ultrasound of the liver revealed a massively enlarged liver with multiple cystic areas.
H. Boonzaaier-Botha, C. Cock
doaj +1 more source
Excisional therapy for benign hepatic lesions [PDF]
With the recent advances in imaging techniques, increased numbers of hepatic lesions are found today, and surgeons are asked frequently for the best course of management. Benign hepatic tumors sometimes cause life-threatening complications and more often
Iwatsuki, S, Starzl, TE, Todo, S
core
The effect of atorvastatin on pancreatic beta cell requirement in women with polycystic ovary syndrome [PDF]
Background There is an increased risk of developing T2DM in women with polycystic ovary syndrome (PCOS) and there is evidence that statins improve metabolic parameters in these patients.
Atkin, Stephen L.+3 more
core +2 more sources