Results 61 to 70 of about 63,834 (278)

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang   +17 more
wiley   +1 more source

Combined oral contraceptives: the optimal range of examination. Part 2

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2018
Combined oral contraceptives are effective drugs for contraception and treatment of reproductive disorders in polycystic ovarian syndrome. The article considers the main laboratory algorithms for excluding the most common endocrine diseases, the clinical
O.V. Rykova
doaj   +1 more source

Antral follicle count and anti-Müllerian hormone level as predictors of ovarian hyperstimulation syndrome in women with polycystic ovarian syndrome undergoing controlled ovarian stimulation

open access: yesJournal of Ultrasonography, 2021
Aim: To compare the rate of ovarian hyperstimulation syndrome in women with and without polycystic ovarian syndrome, and to determine the cut-off for the antral follicle count and the anti-Müllerian hormone level predictive of ovarian hyperstimulation ...
Izhar Rubina   +5 more
doaj   +1 more source

Polycystic Ovary Syndrome: Pathogenesis, health consequences, and treatment of PCOS in relation to insulin resistance [PDF]

open access: yes, 2012
The purpose of this paper is to present a review of the current research on polycystic ovary syndrome (PCOS). PCOS is one of the most common endocrine disorders in women of reproductive age, affecting 5-10% of the population. Despite its prevalence, PCOS
Bernier, Danielle
core   +2 more sources

Associations between anxiety, body mass index, and sex hormones in women [PDF]

open access: yes, 2019
Background: Several studies have shown a positive association between anxiety and obesity, particularly in women. We aimed to study whether sex hormone alterations related to obesity might play a role in this association.
Bae, Y.   +14 more
core   +2 more sources

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

The Endometrial Thickness in Infertile Women with Polycystic Ovarian Syndrome

open access: yesDiyala Journal of Medicine, 2018
Background: The polycystic ovarian syndrome is a common cause of infertility and responsible for many changes in endocrine and metabolic activities with a possible role in changing the endometrial thickness.
Yusra Abdulmahdi Hussein   +1 more
doaj   +2 more sources

Diabetes insipidus in a patient with PCOS treated with Depo-Provera

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2022
Depot medroxyprogesterone acetate, also known as Depo-Provera, is a progesterone-only contraceptive that is administered by injection to patients every three months.
Amanda I Martinez, Nicholas Mezitis
doaj   +1 more source

Perturbations in Lineage Specification of Granulosa and Theca Cells May Alter Corpus Luteum Formation and Function [PDF]

open access: yes, 2019
Anovulation is a major cause of infertility, and it is the major leading reproductive disorder in mammalian females. Without ovulation, an oocyte is not released from the ovarian follicle to be fertilized and a corpus luteum is not formed.
Abedel-Majed, Mohamed A.   +3 more
core   +1 more source

Prenatal hyperandrogenism induces alterations that affect liver lipid metabolism [PDF]

open access: yes, 2016
Prenatal hyperandrogenism is hypothesized as one of the main factors contributing to26 the development of polycystic ovary syndrome (PCOS). PCOS patients have high risk27 of developing fatty liver and steatosis.
Abruzzese, Giselle Adriana   +6 more
core   +2 more sources

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