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Pathophysiological roles of chronic low‐grade inflammation mediators in polycystic ovary syndrome
Journal of Cellular Physiology, 2020Polycystic ovary syndrome (PCOS) is the most common hormonal imbalance disease in reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian overproduction of androgens that lead to severe symptoms such as insulin resistance,
Maryam Rostamtabar +9 more
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Pediatric Annals, 2006
<p>Polycystic ovary syndrome (PCOS) is a heterogeneous familial disorder characterized by hyperandrogenism and chronic anovulation with onset during the peripubertal years. PCOS was initially reported in 1935 as Stein-Leventhal syndrome. Clinical features include amenorrhea, hirsutism, obesity, and enlarged polycystic ovaries.
Constance Y. Baldwin +1 more
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<p>Polycystic ovary syndrome (PCOS) is a heterogeneous familial disorder characterized by hyperandrogenism and chronic anovulation with onset during the peripubertal years. PCOS was initially reported in 1935 as Stein-Leventhal syndrome. Clinical features include amenorrhea, hirsutism, obesity, and enlarged polycystic ovaries.
Constance Y. Baldwin +1 more
openaire +6 more sources
American Journal of Reproductive Immunology, 2020
Polycystic ovary syndrome (PCOS) is associated with endoplasmic reticulum (ER) stress and pro‐inflammatory condition. The aim of the present study was to evaluate the effect of resveratrol treatment on pro‐inflammatory and ER stress markers in patients ...
Samaneh Brenjian +7 more
semanticscholar +1 more source
Polycystic ovary syndrome (PCOS) is associated with endoplasmic reticulum (ER) stress and pro‐inflammatory condition. The aim of the present study was to evaluate the effect of resveratrol treatment on pro‐inflammatory and ER stress markers in patients ...
Samaneh Brenjian +7 more
semanticscholar +1 more source
Endocrinology and Metabolism Clinics of North America, 1997
The cardinal clinical features of PCOS are hirsutism and menstrual irregularity from anovulation. Obesity occurs in approximately 50% of hyperandrogenic anovulatory women, some of whom also have non-insulin-dependent diabetes mellitus. Underlying these clinical findings are several biochemical abnormalities, including LH hypersecretion ...
Daniel A. Dumesic, Vasilios T. Goudas
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The cardinal clinical features of PCOS are hirsutism and menstrual irregularity from anovulation. Obesity occurs in approximately 50% of hyperandrogenic anovulatory women, some of whom also have non-insulin-dependent diabetes mellitus. Underlying these clinical findings are several biochemical abnormalities, including LH hypersecretion ...
Daniel A. Dumesic, Vasilios T. Goudas
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International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2020
To estimate the prevalence of polycystic ovary syndrome (PCOS) among women of reproductive age across educational institutions in the Kashmir valley.
M. Ganie +5 more
semanticscholar +1 more source
To estimate the prevalence of polycystic ovary syndrome (PCOS) among women of reproductive age across educational institutions in the Kashmir valley.
M. Ganie +5 more
semanticscholar +1 more source
The androgenic polycystic ovary
American Journal of Obstetrics and Gynecology, 1976The polycystic ovary has the capacity to produce excessive androgens (delta4-androstenedione, dehydroepiandrosterone, and testosterone). Whether this disorder is caused by constant pituitary priming of the ovaries due to hypothalamic-pituitary derangement or an ovarian enzyme defect, the end result is the same, i.e., abnormal androgen production. In an
Virendra B. Mahesh, Robert B. Greenblatt
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Current Opinion in Pediatrics, 1994
Polycystic ovary syndrome (PCOS) is a complex and still poorly understood process. This review examines current theories regarding the development of PCOS and focuses on the physiologic processes involved in the pubertal and adolescent period and their relationship with pathogenesis of PCOS.
Carlo Flamigni +2 more
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Polycystic ovary syndrome (PCOS) is a complex and still poorly understood process. This review examines current theories regarding the development of PCOS and focuses on the physiologic processes involved in the pubertal and adolescent period and their relationship with pathogenesis of PCOS.
Carlo Flamigni +2 more
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POLYCYSTIC OVARY SYNDROME [PDF]
Endocrinology and Metabolism Clinics of North America, 1998 Polycystic ovary syndrome is a syndrome and not a disease. It reflects multiple potential etiologies and variable clinical presentations that are reviewed in this article. In addition to menstrual dysfunction and hyperandrogenism, women with polycystic ovary syndrome also may have hypothalamic-pituitary abnormalities, polycystic ovaries on pelvic ...
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Polycystic ovaries and obesity
Best Practice & Research Clinical Obstetrics & Gynaecology, 2015Almost 50% of the women with polycystic ovary syndrome (PCOS) are obese. Obesity in PCOS affects reproduction via various mechanisms. Hyperandrogenism, increased luteinizing hormone (LH) and insulin resistance play a pivotal role. Several substances produced by the adipose tissue including leptin, adiponectin, resistin and visfatin may play a role in ...
Ioannis E. Messinis +3 more
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Function of the polycystic ovary
Human Fertility, 2000The mechanism of the increase in the number of follicles in polycystic ovaries (PCO) is still not understood, but most data indicate that folliculogenesis is abnormal at all stages. This increase is probably due to prolonged follicle growth in both ovulatory (ov) and anovulatory PCO (anovPCO) rather than over-recruitment from the primordial stage ...
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