Results 81 to 90 of about 297,437 (356)

Data-driven and Physics Informed Modelling of Chinese Hamster Ovary Cell Bioreactors [PDF]

open access: yesarXiv, 2023
Fed-batch culture is an established operation mode for the production of biologics using mammalian cell cultures. Quantitative modeling integrates both kinetics for some key reaction steps and optimization-driven metabolic flux allocation, using flux balance analysis; this is known to lead to certain mathematical inconsistencies.
arxiv  

The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis.

open access: yesHuman Reproduction, 2016
STUDY QUESTION What is the reported overall prevalence of polycystic ovary syndrome (PCOS) according to the criteria of the National Institutes of Health (NIH), Rotterdam or the Androgen Excess and PCOS Society (AE-PCOS Society)?
G. Bozdag   +4 more
semanticscholar   +1 more source

Identification of crucial genes for polycystic ovary syndrome and atherosclerosis through comprehensive bioinformatics analysis and machine learning

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify potential biomarkers in patients with polycystic ovary syndrome (PCOS) and atherosclerosis, and to explore the common pathologic mechanisms between these two diseases in response to the increased risk of cardiovascular diseases in patients with PCOS.
Lirong Wang   +7 more
wiley   +1 more source

Noncoding RNAs evolutionarily extend animal lifespan [PDF]

open access: yesarXiv, 2023
The mechanisms underlying lifespan evolution in organisms have long been mysterious. However, recent studies have demonstrated that organisms evolutionarily gain noncoding RNAs (ncRNAs) that carry endogenous profound functions in higher organisms, including lifespan.
arxiv  

Proliferating cell nuclear antigen (PCNA) allows the automatic identification of follicles in microscopic images of human ovarian tissue [PDF]

open access: yesPathology and Laboratory Medicine International 2010:2; 99-105, 2010
Human ovarian reserve is defined by the population of nongrowing follicles (NGFs) in the ovary. Direct estimation of ovarian reserve involves the identification of NGFs in prepared ovarian tissue. Previous studies involving human tissue have used hematoxylin and eosin (HE) stain, with NGF populations estimated by human examination either of tissue ...
arxiv   +1 more source

Gynecological surgery in patients with kidney failure on chronic kidney replacement therapy: A binational data linkage study of morbidity and mortality outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates postoperative outcomes of patients with kidney failure on chronic kidney replacement therapy after gynecological surgery. Methods This binational data‐linkage study identified patients with kidney failure via the Australia and New Zealand Dialysis and Transplant Registry who underwent major gynecological ...
Mina Khair   +6 more
wiley   +1 more source

Shapes of the uterine cavity are different in women with polycystic ovary syndrome

open access: yesReproductive Medicine and Biology, 2023
Purpose A cross‐sectional study was conducted to evaluate differences in uterine morphology between women with or without polycystic ovary syndrome. Methods The authors recruited 333 infertile reproductive‐age women including 93 with polycystic ovary ...
Shunsaku Fujii, Takaaki Oguchi
doaj   +1 more source

Genetic Basis of Polycystic Ovary Syndrome (PCOS): Current Perspectives

open access: yesThe Application of Clinical Genetics, 2019
Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant proportion of the global population. It is the main cause of anovulatory infertility in women and is the most common endocrinopathy affecting reproductive-aged ...
M. J. Khan, A. Ullah, S. Basit
semanticscholar   +1 more source

Efficacy of hormone pre‐treatment before ART to improve reproductive outcomes in infertile women with endometriosis: Network meta‐analysis of randomized controlled trials

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Hormone pre‐treatment is still used before assisted reproductive technique (ART) in endometriotic women, but evidence supporting this recommendation is conflicting. Objectives To evaluate whether hormone pre‐treatment with gonadotropin‐releasing hormone (GnRH) agonists or progestogens could improve fertility in women with ...
Gaetano Riemma   +8 more
wiley   +1 more source

Modeling Vascular Branching Alterations in Polycystic Kidney Disease [PDF]

open access: yesarXiv, 2022
The analysis of biological networks encompasses a wide variety of fields from genomic research of protein-protein interaction networks, to the physiological study of biologically optimized tree-like vascular networks. It is certain that different biological networks have different optimization criteria and we are interested in those networks optimized ...
arxiv  

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