Cigarette smoking induces relative and absolute erythrocytosis (smokers' polycythemia). In patients with smokers' polycythemia complicated by chronic obstructive pulmonary disease, the incidence and mortality rate of pulmonary embolism increase ...
Kazuhide Iizuka +17 more
doaj +2 more sources
Papel de la activación leucocitaria y plaquetaria en la trombosis de los síndromes mieloproliferativos crónicos [PDF]
[spa] INTRODUCCIÓN Y OBJETIVOS: La causa fundamental de la trombosis en la policitemia vera y la trombocitemia esencial es el aumento de la viscosidad sanguínea secundaria a la eritrocitosis así como el incremento del número de plaquetas y las ...
Álvarez Larrán, Alberto
core +6 more sources
Breaking stereotypes - Polycythemia secondary to shisha smoking in a middle-age Swiss woman. [PDF]
The diagnosis of polycythemia, particularly the secondary forms, can be challenging. The distinction between primary and secondary polycythemia is relevant and has management implications.
Rovó, Alicia, Agbariah, Nada
core +2 more sources
Studies of JAK2 mutations in myeloproliferative disorders [PDF]
Myeloproliferative disorders (MPD) are diseases characterized by clonal hematopoiesis with overprodution of mature cells from erythroid, megakaryocytic and myeloid lineages.
Li, Sai
core +1 more source
The haematocrit and platelet target in polycythemia vera [PDF]
Polycythemia vera (PV) is a chronic myeloproliferative disorder whose major morbidity and mortality are thrombohaemorragic events and progression to acute leukaemia or myelofibrosis.
Di Nisio M +14 more
core +1 more source
JAK2 Variant and Parkinsonian Syndromes: Coincidence or Pathophysiological Link? [PDF]
Abstract Background JAK2 variants are a hallmark of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythemia. These disorders are often associated with thrombotic and inflammatory complications. From a movement disorder perspective, chorea is a rare but well‐recognized neurological occurrence in this context ...
Jurado E +5 more
europepmc +2 more sources
Association of subcutaneous testosterone pellet therapy with developing secondary polycythemia
A variety of methods for testosterone replacement therapy (TRT) exist, and the major potential risks of TRT have been well established. The risk of developing polycythemia secondary to exogenous testosterone (T) has been reported to range from 0.4% to 40%
Katherine Lang Rotker +6 more
doaj +1 more source
Performance of Antenatal Diagnostic Criteria of Twin-Anemia-Polycythemia Sequence. [PDF]
This study aims to elicit the validation performance of different diagnostic criteria and to evaluate the disease course and perinatal outcomes of pregnancies complicated by twin anemia polycythemia sequence (TAPS).
Erkan Kalafat +14 more
core +1 more source
PREFERENTIAL NUCLEAR ACCUMULATION OF JAK2V617F IN CD34+ BUT NOT IN GRANULOCYTIC, MEGAKARYOCYTIC OR ERYTHROID CELLS OF PATIENTS WITH PHILADELPHIA-NEGATIVE MYELOPROLIFERATIVE NEOPLASIA. [PDF]
Recently, Dawson et al. identified a previously unrecognized nuclear role for JAK2 in the phosphorylation of the tyrosine 41 of the histone H3 with the exclusion of HP1a from chromatin and resulting in a disregulation of several JAK2-regulated genes such
Rinaldi, Ciro Roberto
core +2 more sources

