Results 121 to 130 of about 282,663 (297)

Clonal heterogeneity as a driver of disease variability in the evolution of myeloproliferative neoplasms. [PDF]

, 2014
Myeloproliferative neoplasms (MPNs) are clonal hematological diseases in which cells of the myelo-erythroid lineage are overproduced and patients are predisposed to leukemic transformation.
de Haan, Gerald, Green, Anthony R, Kent, David G, Prick, Janine   +3 more
core   +1 more source

Safety and efficacy of combination therapy of interferon‐α2 and ruxolitinib in polycythemia vera and myelofibrosis

Cancer Medicine, 2018
Interferon‐α2 reduces elevated blood cell counts and splenomegaly in patients with myeloproliferative neoplasms (MPN) and may restore polyclonal hematopoiesis.
S. U. Mikkelsen, L. Kjaer, M. E. Bjørn, T. Knudsen, A. Sørensen, C. Andersen, O. Bjerrum, Nana Brochmann, D. Fassi, T. Kruse, T. Larsen, H. T. Mourits-Andersen, C. Nielsen, N. Pallisgaard, M. Thomassen, V. Skov, H. Hasselbalch   +16 more
semanticscholar   +1 more source

Non-adherence to treatment with cytoreductive and/or antithrombotic drugs is frequent and associated with an increased risk of complications in patients with polycythemia vera or essential thrombocythemia (OUEST study)

Haematologica, 2018
The purpose of this study was to identify the incidence, causes and impact of non-adherence to oral and subcutaneous chronic treatments for patients with polycythemia vera or essential thrombocythemia.
Ronan Le Calloch, Karine Lacut, Christelle Le Gall-Ianotto, Emmanuel Nowak, Morgane Abiven, Adrian Tempescul, Florence Dalbies, Jean-Richard Eveillard, Valérie Ugo, Stéphane Giraudier, Gaëlle Guillerm, Eric Lippert, Christian Berthou, Jean-Christophe Ianotto   +13 more
doaj   +1 more source

Whole-exome sequencing identifies novel candidate predisposition genes for familial polycythemia vera [PDF]

, 2017
Background: Polycythemia vera (PV), characterized by massive production of erythrocytes, is one of the myeloproliferative neoplasms. Most patients carry a somatic gain-of-function mutation in JAK2, c.1849G > T (p.Val617Phe), leading to constitutive ...
Aaltonen, Lauri A., Hemminki, Kari, Hirvonen, Elina A. M., Kilpivaara, Outi, Pitkanen, Esa   +4 more
core   +1 more source

CLINICAL STUDIES OF THE BLOOD VOLUME. VIII. MACROCYTIC AND HYPOCHROMIC ANEMIAS DUE TO CHRONIC BLOOD LOSS, HEMOLYSIS AND MISCELLANEOUS CAUSES, AND POLYCYTHEMIA VERA 1 [PDF]

, 1939
John G. Gibson, Alfred W. Harris, Verne W. Swigert   +2 more
openalex   +1 more source

How to manage polycythemia vera [PDF]

Leukemia, 2011
My diagnostic approach in case of isolated erythrocytosis is based on the visit and the interview of patients, and on checking the causes of secondary erythrocytosis. If causes of secondary erythrocytosis are not evident and serum erythropoietin level is low-normal, I study JAK2 mutations. In the case of a patient with erythrocytosis and other signs of
openaire   +3 more sources

PULMONARY GAS DIFFUSION IN POLYCYTHEMIA VERA [PDF]

, 1927
George A. Harrop, Elmer H. Heath, Bianca Schaub   +2 more
openalex   +1 more source

Value of cytogenetic abnormalities in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a study of the MYSEC project

Haematologica, 2018
Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms (MPN)[1][1] that can progress to blast phase[2][2] and to post-PV (PPV) myelofibrosis (MF) and post-ET (PET) MF,[3][3] from now on referred to as secondary ...
B. Mora, T. Giorgino, P. Guglielmelli, E. Rumi, M. Maffioli, A. Rambaldi, M. Caramella, R. Komrokji, J. Gotlib, J. Kiladjian, F. Cervantes, T. Devos, F. Palandri, V. De Stefano, M. Ruggeri, R. Silver, G. Benevolo, F. Albano, C. Cavalloni, D. Barraco, M. Merli, D. Pietra, R. Casalone, T. Barbui, G. Rotunno, M. Cazzola, A. Vannucchi, F. Passamonti   +27 more
semanticscholar   +1 more source

Allogeneic hematopoietic stem cell transplantation in patients with polycythemia vera or essential thrombocythemia transformed to myelofibrosis or acute myeloid leukemia: a report from the MPN Subcommittee of the Chronic Malignancies Working Party of the European Group for Blood and Marrow Transplantation

Haematologica, 2014
The clinical course of polycythemia vera and essential thrombocythemia is potentially associated with long-term severe complications, such as evolution to myelofibrosis or acute myeloid leukemia. Allogeneic stem cell transplantation is currently the only
Federico Lussana, Alessandro Rambaldi, Maria Chiara Finazzi, Anja van Biezen, Marijke Scholten, Elena Oldani, Alessandra Carobbio, Simona Iacobelli, Jurgen Finke, Arnon Nagler, Liisa Volin, Thierry Lamy, Renate Arnold, Mohamad Mohty, Mauricette Michallet, Theo de Witte, Eduardo Olavarria, Nicolaus Kröger   +17 more
doaj   +1 more source

In vivo localization of colloidal Au198 intravenously injected in polycythemia vera [PDF]

, 1958
L. Engstedt, S. Franzén, Lars Jonsson, Lars‐Gunnar Larsson   +3 more
openalex   +1 more source