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Genetic overview of postaxial polydactyly: Updated classification

Clinical Genetics, 2022
Polydactyly or polydactylism, also known as a hyperdactyly, is a congenital limb defect with various morphologic phenotypes. Apart from physical and functional impairments, the presence of polydactyly is an indication of an underlying syndrome in the ...
Zaheer Ahmad   +7 more
semanticscholar   +1 more source

Radial Polydactyly

JBJS Reviews, 2022
» Radial polydactyly is one of the most common congenital anomalies of the hand, with an incidence of 0.08 to 1.40 per 1,000 live births; it requires surgical treatment early in life.» Polydactyly occurs during weeks 5, 6, 7, and 8 of embryogenesis, principally due to misregulation of the sonic hedgehog protein within the ...
Nathan, Khabyeh-Hasbani   +3 more
openaire   +2 more sources

BMSC-derived exosomes from congenital polydactyly tissue alleviate osteoarthritis by promoting chondrocyte proliferation

open access: yesCell Death Discovery, 2020
In the past decade, mesenchymal stem cells (MSCs) have been widely used for the treatment of osteoarthritis (OA), and exosomes may play a major role. Here, we acquired a special kind of MSCs from the bone marrow of surgically resected tissue from the ...
Xinghua Zhou   +8 more
exaly   +2 more sources

Polydactyly of the Foot: A Review.

Journal of the American Academy of Orthopaedic Surgeons, 2021
Pediatric foot polydactyly presents in a wide variety of deformities from single extra digits attached only by a narrow soft-tissue connection to complex central foot duplications with tarsal bone duplication.
D. Kelly, K. Mahmoud, Benjamin M. Mauck
semanticscholar   +1 more source

Characterization of polydactyly chondrocytes and their use in cartilage engineering

open access: yesScientific Reports, 2019
Treating cartilage injuries and degenerations represents an open surgical challenge. The recent advances in cell therapies have raised the need for a potent off-the-shelf cell source.
Nicolas Broguiere   +2 more
exaly   +2 more sources

Polydactyly of the thumb: a modification of the Wassel-Flatt classification

Journal of Hand Surgery (European Volume), 2021
Although the Wassel-Flatt classification system has been widely used for radial polydactyly, it has some limitations. We modified the classification system by introducing the hypoplastic types and refining the definition of triphalangeal thumb without ...
Jae Kwang Kim   +3 more
semanticscholar   +1 more source

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