Results 71 to 80 of about 17,999 (210)
Ciliary Defects in Inherited Retinal Diseases
Advanced Genetics, Volume 7, Issue 1, March 2026.The photoreceptor cilium is a specialized sensory organelle essential for vision. This review systematically summarizes the structural and functional defects of the cilium that lead to inherited retinal diseases (IRDs). It highlights key pathogenic genes, elucidates molecular mechanisms of degeneration, and evaluates emerging therapeutic strategies ...
Guizhi Guo, Lin Li, Jun Zhou, Jie Ran
wiley +1 more source
Inflammation and Regeneration, 2017 BackgroundWe previously conducted a first-in-human clinical study of articular cartilage repair using autologous chondrocyte sheets and confirmed the regeneration of hyaline-like cartilage in all eight patients.
M. Maehara +6 more
semanticscholar +1 more source
A dominant missense variant within LMBR1 related to equine polydactyly
Communications BiologyPolydactyly was recorded before 100 BCE and attracted widespread interest because of its relationship to limb health and ancestral traits in horses. However, the underlying reasons for the development of polydactyly remain unclear.
Yue Luan +7 more
doaj +1 more source
Pregnancy, Volume 2, Issue 2, March 2026.Abstract Non‐immune hydrops fetalis (NIHF) can result from a multitude of underlying causes, such as fetal genetic diseases, congenital anomalies, infections, fetal arrhythmias, placental tumors, monochorionic twin complications, and other disorders.
Society for Maternal‐Fetal Medicine (SMFM) +3 more
wiley +1 more source
Cilia, 2017 BackgroundSkeletal ciliopathies comprise a spectrum of ciliary malfunction disorders that have a profound effect on the skeleton. Most common among these disorders is short rib polydactyly syndrome (SRPS), a recessively inherited perinatal lethal ...
Ivan Duran +12 more
semanticscholar +1 more source
Epidemiology of hypospadias in China: A nationwide surveillance‐based study, 2010–2020
Andrology, Volume 14, Issue 3, Page 880-889, March 2026.Abstract Background The prevalence of hypospadias varied internationally. However, epidemiological data on hypospadias in contemporary China remain limited. Objectives We aim to examine the epidemiological characteristics of hypospadias in Chinese population.
Chen Zhiyu +7 more
wiley +1 more source
Andrology, Volume 14, Issue 3, Page 661-701, March 2026.Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani +6 more
wiley +1 more source
Identification of truncated variants in GLI family zinc finger 3 (GLI3) associated with polydactyly
Journal of Orthopaedic Surgery and ResearchBackground Polydactyly is a prevalent congenital anomaly with an incidence of 2.14 per 1000 live births in China. GLI family zinc finger 3 (GLI3) is a classical causative gene of polydactyly, and serves as a pivotal transcription factor in the hedgehog ...
Run-Yan Wang +6 more
doaj +1 more source
Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 441-452, March 2026.Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.70022 This original article is commented on by Scelsa on pages 311–312 of this issue. Abstract Aim To examine the accuracy of prenatal counselling at a multidisciplinary fetal neurology clinic (FNC) that led to termination of pregnancy (TOP), to improve the quality of future ...
Avi Shariv +12 more
wiley +1 more source
Thumb Polydactyly: Clinical Outcome after Reconstruction
Journal of Orthopaedic Surgery, 2006 Purpose. To evaluate clinical and cosmetic outcomes of reconstruction in thumb polydactyly and prognostic value of the Wassel classification. Methods.
CH Yen, WL Chan, HB Leung, KH Mak
doaj +1 more source