Results 81 to 90 of about 2,024 (141)
Recent Progress in Marine Toxin Rsearch
, 1982 A series of toxins isolated from the dinoflagellates, Gonyaulax spp., sheds new light on the structure of the receptors on excitable membranes. Biosynthetic origins of these toxins and tetrodotoxin, another sodium channel-specific marine toxin, are ...
Shimizu, Yuzuru
core +1 more source
The Claisen rearrangement approach to fused bicyclic medium-ring oxacycles.
, 2008 The synthesis of five fused-bicyclic medium-ring lactones carrying identical ring-fusion to that in the polyether toxins is described using an enolate hydroxylation, intramolecular hydrosilation, Claisen rearrangement ...
O'Sullivan, Paul +15 more
core +1 more source
, 2016 A stereoselective method for the synthesis of substituted tetrahydropyran derivatives employing a tandem SN2−Michael addition sequence to vinylogous carbonates is developed.
S. Raja Bhushan Reddy (2368132) +1 more
core +1 more source
Biological activities of aqueous and organic extracts from tropical marine sponges
, 2010 We report on screening tests of 66 extracts obtained from 35 marine sponge species from the Caribbean Sea (Curaçao) and from eight species from the Great Barrier Reef (Lizard Island). Extracts were prepared in aqueous and organic solvents and were tested
Dietrich Mebs +7 more
core +1 more source
Cationic Zirconocene Mediated Cascade Synthesis of Tetrahydrofurans [PDF]
, 2005 Tetrahydrofurans and tetrahydropyrans are common structural features of numerous natural products, most notably the marine toxins and the polyether antibiotics, such brevetoxin and monensin.
Mignone, James
core
, 1996 Seven- to 8-day-old Arc/Swiss mice were infected with 100,000-120,000 Cryptosporidium parvum oocysts. At 8 days postinfection (PI) the jejunum, ileum, cecum, colon, and rectum were removed.
Meloni, B.P., Thompson, R.C.A.
core
, 2016 Ciguatoxins, the principal causative toxins of ciguatera seafood poisoning, are large ladder-like polycyclic ethers. We report a highly stereoselective 6-exo radical cyclization/ring-closing olefin metathesis sequence to construct the syn/trans-fused ...
Shuji Yamashita (436915) +6 more
core +1 more source
Review Ciguatoxins: Cyclic Polyether Modulators of Voltage-gated Iion Channel Function
, 2014 : Ciguatoxins are cyclic polyether toxins, derived from marine dinoflagellates, which are responsible for the symptoms of ciguatera poisoning. Ingestion of tropical and subtropical fin fish contaminated by ciguatoxins results in an illness characterised ...
Graham M. Nicholson, Richard J. Lewis
core
Self-Assembly of Okadaic Acid as a Pathway to the Cell
, 2016 The polyether toxin okadaic acid (OA) inhibits several protein serine/threonine phosphatases that play central roles in the regulation of many essential cellular processes.
Antonio Hernández Daranas (2473177) +4 more
core +1 more source
Automatic MS/MS Data Mining Strategy for Rapid Screening of Polyether Toxins Derived from <i>Gambierdiscus</i> Species. [PDF]
Anal ChemLiu X +6 more
europepmc +1 more source