Results 171 to 180 of about 28,074 (323)

Systemic Inflammation Modulates Clearance and Drives Extra‐Hepatic Distribution of Extracellular Vesicles

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Extracellular vesicles (EVs) are promising vehicles for targeted therapeutic delivery, capable of encapsulating and transporting biomolecules to specific cells and tissues. Given that inflammation is central to many acute and chronic diseases, understanding EV biodistribution under inflammatory conditions is essential for therapeutic ...
Svetlana Pavlova   +19 more
wiley   +1 more source

Magnetic‐Assisted Aptamer Selection and Isolation of Migrasomes for Application in Lung Adenocarcinoma Proteomic Analysis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
Mag‐SELEX identified the first aptamer targeting migrasome, offering a potential ligand for their identification and detection in clinical samples. The magnetic aptamer probe, characterised by high specificity and rapid recovery, provides a simple, rapid, and economical method for elucidating migrasome mechanisms in disease and facilitating ...
Yixin Xu   +12 more
wiley   +1 more source

Oxymatrine Inhibits Epithelial‐Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF‐β1/Smad Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 4, April 2026.
ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley   +1 more source

Radiocarbon analysis reveals the contribution of aged terrestrial carbon to sedimentary methane cycling

open access: yesLimnology and Oceanography, Volume 71, Issue 4, April 2026.
Abstract Methane (CH4) production in lacustrine sediments is known to be spatially heterogeneous, varying both horizontally and vertically. Porewater methane concentrations often differ between locations within a lake and with depth within the sediment profile. The drivers of this heterogeneity are often not well understood.
Sigrid van Grinsven   +10 more
wiley   +1 more source

Sediment trap preservative choice impacts particle‐associated microbial community composition

open access: yesLimnology and Oceanography: Methods, Volume 24, Issue 4, April 2026.
Abstract Understanding and quantifying the microbial contribution to particulate organic matter (POM) flux and carbon cycling in the ocean relies largely on the collection of sinking POM. A critical aspect of evaluating microbial communities on sediment trap‐collected POM is their preservation until recovery and sample processing.
Nicola L. Paul   +7 more
wiley   +1 more source

Low Dosage of ABA Enhances Arbuscule Formation and Recovers the Inhibitory Effect of Low pH on This Process

open access: yesPlant-Environment Interactions, Volume 7, Issue 2, April 2026.
ABSTRACT Arbuscular mycorrhizal (AM) fungi can form symbiotic associations with plants and play a significant role in enhancing plant tolerance to acidic stress, wherein arbuscules serve as key structures in this process. However, the response patterns of arbuscule development and function under low pH conditions remain poorly understood.
Xiaodi Liu   +5 more
wiley   +1 more source

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