AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li +6 more
wiley +1 more source
A retrospective comparative evaluation of rectal preparation strategies for patients undergoing stereotactic body radiotherapy for prostate cancer. [PDF]
Tran MN +9 more
europepmc +1 more source
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang +6 more
wiley +1 more source
PEGylated Proteins: How Much Does Molecular Weight Matter? [PDF]
Fornasari DMM.
europepmc +1 more source
Stabilization of Polyethylene Glycol in Archaeological Wood [PDF]
Mortensen, Martin Nordvig
core
Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li +22 more
wiley +1 more source
Evaluation of Plasma Polyethylene Glycol (PEG) Levels in a Healthy Adult Population. [PDF]
Kubesch K +4 more
europepmc +1 more source
Growth‐Like Swelling of 2D Precursors for Efficient Fabrication of Complex 3D Microstructures
The growth‐like swelling process fills photocured polymers into the elastomeric microstructures, inducing a significant swelling deformation of microstructures that can be maintained in the absence of solvents. The growth‐like swelling process breaks through the dependence of swelling deformation on the solvents, thereby expanding the application of 3D
Xinkai Zhu +13 more
wiley +1 more source
Synthesis, antimicrobial, antioxidant studies of thermally stable nanocomposite films doped with CoO-NPs for active food packaging applications. [PDF]
Ali M, Khosa MK, Noor A, Qayyum S.
europepmc +1 more source
Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source

