Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
INFLUENCE OF COCONUT SHELL ADDITION ON PHYSICO-MECHANICAL PROPERTIES OF WOOD PLASTIC COMPOSITES1
In this study, composites with three types of thermoplastic matrix and cellulosic material in a proportion of 40% were produced. The three thermoplastic matrices were high density polyethylene (HDPE), polypropylene (PP) and low density polyethylene (LDPE)
Éverton Hillig +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Polimer Malzemelerin Sürtünme Karıştırma Nokta Kaynağı
Polimer malzemeler çeşitli endüstriyel alanlarında kullanılan mühendislik malzemeleridir. Teknolojinin ilerlemesiyle birlikte polimer işleme ve üretim teknikleri de gelişmiştir.
Bekir Çevik
doaj
Synthesis and Deconstruction of Polyethylene-type Materials
Polyethylene deconstruction to reusable smaller molecules is hindered by the chemical inertness of its hydrocarbon chains. Pyrolysis and related approaches commonly require high temperatures, are energy-intensive, and yield mixtures of multiple classes of compounds. Selective cleavage reactions under mild conditions (
Schwab, Simon T. +3 more
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Investigations of Electrical Trees in the Inner Layer of XLPE Cable Insulation Using Computer-aided Image Recording Monitoring [PDF]
Using a computer-aided image recording monitoring system, extensive measurements have been performed in the inner layer of 66 kV cross-linked polyethylene (XLPE)cables.
Li, Shengtao +7 more
core +1 more source
Stadying mechanical properties for polyethylene composites rein for by fish shell particles [PDF]
In this research we use both High Density Polyethylene (HDPE), and Low Density Polyethylene (LDPE)were used as matrix to the composite material and fish shell particles were used as a reinforced filler, Plunger injection molding method were used to ...
doaj +1 more source
Osteoproperties of polyethylene glycol hydrogel material
Aim The aim of the present study was to test the osteogenic potential of a synthetic hydrogel made of polyethylene glycol (PEG), loaded with adult mesenchymal stem cells, used as a biodegradable membrane for guided bone regeneration (GBR). Materials and methods Adult mesenchymal stem cells derived from adipose tissue (ADSCs) were isolated ...
LOPS, DIEGO +9 more
openaire +2 more sources

