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Polygenic risk scores in bipolar disorder subgroups
Journal of Affective Disorders, 2015Bipolar disorder (BD) is a genetically and clinically heterogeneous disorder. Current classifications of BD rely on clinical presentations without any validating biomarkers, making homogenous and valid subtypes warranted. This study aims at investigating whether a BD polygenic risk score (PGRS) can validate BD subtypes including diagnostic sub ...
Sofie Ragnhild, Aminoff +7 more
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Polygenic risk scores for CARDINAL study
Nature Genetics, 2022Clement A. Adebamowo +18 more
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A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease
Nature Medicine, 2023Aniruddh Pradip Patel +2 more
exaly
[Polygenic scores and cancer risk].
Medecine sciences : M/S, 2020Risk assessment for a cancer type with moderate heritability can be accurately performed using a relatively small number of SNPs detected by GWAS analyses to calculate a polygenic risk score (PRS) that has definite clinical utility.
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Genome-wide polygenic score to predict chronic kidney disease across ancestries
Nature Medicine, 2022Atlas Khan +2 more
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Novel Polygenic Risk Score for Intracranial Aneurysms
Stroke, 2023Simon Frerich, John W. Cole
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