Results 171 to 180 of about 2,976,187 (391)
American Journal of Psychiatry, 2019 OBJECTIVE Different cognitive development histories in schizophrenia may reflect variation across dimensions of genetic influence. The authors derived and characterized cognitive development trajectory subgroups within a schizophrenia sample and profiled
D. Dickinson +5 more
semanticscholar +1 more source
Shared Genetics of Psychiatric Disorders [PDF]
, 2019 Until recently, advances in understanding the genetic architecture of psychiatric disorders have been impeded by a historic, and often mandated, commitment to the use of traditional, and unvalidated, categorical diagnoses in isolation as the relevant ...
Fuller, Tova, Reus, Victor
core
Psychiatric genetics and the structure of psychopathology [PDF]
, 2018 For over a century, psychiatric disorders have been defined by expert opinion and clinical observation. The modern DSM has relied on a consensus of experts to define categorical syndromes based on clusters of symptoms and signs, and, to some extent ...
Andreassen, Ole A. +5 more
core +1 more source
The Plant Genome, Volume 15, Issue 4, December 2022., 2022 Abstract The success of genomic selection (GS) in breeding schemes relies on its ability to provide accurate predictions of unobserved lines at early stages. Multigeneration data provides opportunities to increase the training data size and thus, the likelihood of extracting useful information from ancestors to improve prediction accuracy.
Marco Lopez‐Cruz +12 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective Genetic testing is now included in the diagnostic assessment of childhood onset epilepsies. We evaluated the yield of a targeted next generation sequencing (TNGS) panel dedicated to pediatric epilepsies. Methods We tested by TNGS panel 1000 consecutive patients presenting with childhood onset epilepsies and including mainly patients ...
Giulia Barcia +21 more
wiley +1 more source
Alfalfa genomic selection for different stress‐prone growing regions
The Plant Genome, Volume 15, Issue 4, December 2022., 2022 Abstract Alfalfa (Medicago sativa L.) selection for stress‐prone regions has high priority for sustainable crop–livestock systems. This study assessed the genomic selection (GS) ability to predict alfalfa breeding values for drought‐prone agricultural sites of Algeria, Morocco, and Argentina; managed‐stress (MS) environments of Italy featuring moderate
Paolo Annicchiarico +9 more
wiley +1 more source
bioRxiv, 2019 Background Increasing childhood overweight and obesity rates are associated with not only adverse physical, but also mental health outcomes, including depression.
Reut Avinun, A. Hariri
semanticscholar +1 more source
Can artificial neural networks supplant the polygene risk score for risk prediction of complex disorders given very large sample sizes? [PDF]
arXiv, 2019 Genome-wide association studies (GWAS) provide a means of examining the common genetic variation underlying a range of traits and disorders. In addition, it is hoped that GWAS may provide a means of differentiating affected from unaffected individuals. This has potential applications in the area of risk prediction.
arxiv
Advanced Genetics, EarlyView.Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li +13 more
wiley +1 more source