Results 131 to 140 of about 27,242,528 (312)

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

Advanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu, Yue Xi, Sheng Wang, Ye Chen, Jiajie Yang, Xiaojian Shi   +5 more
wiley   +1 more source

In Situ Generation of Gel Foam via Heat‐Accelerated Calcium Ion Release From Nano‐CaCO3 for Lithium‐Ion Battery Fire Suppression and Prevention

Advanced Science, EarlyView.
We present a heat‐accelerated in situ crosslinking strategy to create an alginate gel foam for lithium‐ion battery fire suppression. At ambient temperature, the formulation maintains low viscosity for easy foam generation. After exposure to fire, δ‐gluconolactone hydrolysis accelerates, enabling rapid Ca2+ release from CaCO3 and rapid ionic ...
Xiaoyang Yu, Cuiping Li, Mingjun Xu, Man Pun Wan   +3 more
wiley   +1 more source

Mesh morphing-based pre-processing and numerical simulation of blockage accident in lead–bismuth fast reactor fuel assembly

Nuclear Engineering and Technology
This paper presents a CFD modeling approach for a 19-rod bundle fuel assembly with spiral semi-cylindrical ribs, which potentially can be used for liquid metal cooled fast reactor, as well as a numerical simulation of flow and thermal behavior under ...
Hao Sun, Yong Ouyang, Zihua Liu, Huo Liang, Hanyan Luo, Zhikang Lin   +5 more
doaj   +1 more source

A Dual‐Functional Nanoplatform Targeting the dsDNA–cGAS Axis to Mitigate Disc Degeneration and Aberrant Innervation

Advanced Science, EarlyView.
RU@PEI‐ZIF integrates dsDNA scavenging with local cGAS inhibition to suppress the dsDNA–cGAS–STING/Netrin‐1 axis in intervertebral disc degeneration. By attenuating nucleus pulposus cell senescence, inflammatory and matrix‐catabolic responses, and pathological sensory innervation, this dual‐functional nanoplatform preserves disc integrity and reduces ...
Zhaojun He, Tianyu Chen, Zezheng Liu, Xinlin Huang, Ruitangbin Jiang, Yihao Liu, Baojing Xu, Yuxiang Li, Kangning Zhao, Huibo Yan, Lei Zhou, Can Liu, Qingchu Li   +12 more
wiley   +1 more source

A polyhedral approach to computing border bases

, 2009
Border bases can be considered to be the natural extension of Gröbner bases that have several advantages. Unfortunately, to date the classical border basis algorithm relies on (degree-compatible) term orderings and implicitly on reduced Gröbner bases.
Braun, Gábor, Pokutta, Sebastian
openaire   +2 more sources

An Interactive Polyhedral Approach for Multi-objective Combinatorial Optimization with Incomplete Preference Information

Scalable Uncertainty Management, 2019
Nawal Benabbou, T. Lust
semanticscholar   +1 more source

Mechanochemical Engineered Sulfur Copolymers Onto Group 13 and Related Fillers Through Lewis Acid‐Base Pairing

Advanced Science, EarlyView.
Green mechanochemical copolymerization was developed for universal interfacial modification of Group 13 and related fillers. By leveraging Lewis acid–base coordination to anchor sulfur‐containing polymers—validated via multiscale characterization and DFT—this versatile method boosts performance across liquid fuels, thermal‐shielding materials, and ...
Chen Wang, Xiaoyang Shao, Zixuan Lei, Ruoqing Zhao, Xiaozhong Bao, Shuiping Zhou, Wen Ao, Zhenhua Wang   +7 more
wiley   +1 more source

Mn/Zn Bimetallic MOF‐Integrated Hydrogel Alleviates Excessive Mitochondrial Fission in BMSCs to Promote Osteoporotic Jawbone Repair

Advanced Science, EarlyView.
Excessive reactive oxygen species (ROS) and chronic inflammation impair bone marrow‐derived mesenchymal stem cells (BMSCs), contributing to poor healing in osteoporotic jawbone defect. The gelatin methacryloyl hydrogel loaded with manganese‐doped zeolitic imidazolate framework (Mn‐ZIF‐8@GelMA) promotes regeneration through redox regulation and ...
Xiayue Jin, Shengjia Ye, Yun Yuan, Xueying Yang, Jiarui Cui, Hongming Zhang, Hui Huang   +6 more
wiley   +1 more source

To Be or Not to Be Eutectic: Anomalous Glass Forming Ability Governed by Melt Structural Complexity

Advanced Science, EarlyView.
Challenging the eutectic rule, congruently melting Ti–Cu alloys show greater glass‐forming ability than their eutectic counterparts. This arises from the congruent melt's structural complexity: higher cluster diversity and stronger inter‐cluster correlations from entropy–enthalpy competition.
Wei Chen, Xuerui Wei, Chengzhe Wang, Zhichao Lu, Fan Zhang, Yan Huang, Yibo Zhang, Liang Wang, Saichao Cao, Chunyin Zhou, Ke Yang, Zhendong Fu, Jinkui Zhao, Dongbai Sun, Fanqiang Meng, Zhou Zhou, Xun‐li Wang, Weihua Wang, Dong Ma   +18 more
wiley   +1 more source

Molecularly Engineered Nitrate Double Perovskites with Elevated Ferroelectric Phase Transition Temperature and Large Piezoelectric Response

Advanced Science, EarlyView.
This study reports molecularly engineered nitrate double perovskites based on systematic BI‐site cation substitution. This molecular engineering modulates local BI···NO3 interactions, nitrate connectivity, and collective physical responses, accompanied by structural conversion from mixed corner‐/face‐sharing structures to three‐dimensional corner ...
Le Ye, Guang‐Yuan Hu, Yarou Duan, Yutong Lin, Ding‐Chong Han, Zi‐Luo Fang, Zhe Dong, Wei‐Xiong Zhang, Liang‐Han Shen, Na Wang, Le‐Ping Miao, Heng‐Yun Ye, Lingling Mao   +12 more
wiley   +1 more source