Results 91 to 100 of about 763,041 (124)

Polyisoprenyl phosphates in intracellular signalling

open access: yesNature, 1997
In response to environmental stimuli, leukocyte membrane remodelling generates biologically active lipids that can serve as both intra- and extracellular mediators. There are several classes of lipids that can mediate inflammatory reactions. We report here on a new intracellular lipid signal that regulates oxygen-radical formation in neutrophils, a key
B D, Levy, N A, Petasis, C N, Serhan
semanticscholar   +4 more sources
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Characterization of Mannolipids Formed in a Calf Pancreatic Microsomal Fraction from Guanosine Diphosphate [14C]Mannose and either Endogenous Lipid or Exogenous Polyisoprenyl Phosphates

Biochemical Society Transactions, 1973
In some glycoproteins, a glycosylamine bond between 2-acetamido-2-deoxy-~-glucose and the amide group of asparagine serves to link oligosaccharide with peptide. A common oligosaccharide unit containing 2-acetamido-2-deoxy-~-glucose and D-mannose residues has been suggested for the linkage region of these glycoproteins (Lee & Scocca, 1972).
Jan S Tkacz   +2 more
exaly   +3 more sources

Glycan ligation reactions in the periplasmic space

open access: yes, 2020
The biosynthesis pathways of bacterial glycoconjugate molecules, especially of those molecules that traffic across the cytoplasmic membrane and reside extracytoplasmically has biologically conserved features including the saccharides are formed as lipid ...
M. Valvano
semanticscholar   +2 more sources

Polyisoprenyl Phosphate Signaling: Topography in Human Neutrophils

Biochemical and Biophysical Research Communications, 2000
To determine the relationship of polyisoprenyl phosphate (PIPP) remodeling and signaling to the activation state of human neutrophils (PMN), we examined the impact of leukotriene B(4) (LTB(4)) on the conversion of a unique bioactive isoprenoid (presqualene diphosphate: PSDP), recently identified as a novel endogenous signaling molecule.
Bruce D Levy, Charles N Serhan
exaly   +3 more sources

Biochemical and molecular dynamics studies of archaeal polyisoprenyl pyrophosphate phosphatase from Saccharolobus solfataricus

Enzyme and Microbial Technology, 2020
The undecaprenyl pyrophosphate phosphatase (UppP) is an integral membrane pyrophosphatase. In bacteria, UppP catalyzes the dephosphorylation of undecaprenyl pyrophosphate (C55-pp) to undecaprenyl phosphate (C55-P) in the periplasmic space, which is an ...
Chia-Cheng Chou   +2 more
exaly   +2 more sources

Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a ‘stop’ signaling switch for aspirin‐triggered lipoxin A 4

The FASEB Journal, 1999
ABSTRACT It is of wide interest to understand how opposing extracellular signals (positive or negative) are translated into intracellular signaling events. Receptor–ligand interactions initiate the generation of bioactive lipids by human neutrophils (PMN), which serve as signals to orchestrate cellular responses ...
B D, Levy   +5 more
openaire   +3 more sources

An electrospray-ionization tandem mass spectrometry method for determination of the anomeric configuration of glycosyl 1-phosphate derivatives.

open access: yesAnalytical Biochemistry, 1998
A rapid, simple, and sensitive method is described for the determination of the anomeric configuration of sugar 1-phosphates, sugar nucleotides, and polyisoprenyl-phospho-sugars.
B. A. Wolucka   +4 more
semanticscholar   +2 more sources

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