Results 131 to 140 of about 3,118,170 (360)

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

A three-component theory of sedimentation equilibrium in a density gradient [PDF]

, 1961
In the original analysis (1) of the behavior of macromolecules and viruses in a density gradient at equilibrium in the ultracentrifuge, only two incompressible components were considered to be present.
Hearst, John E., Vinograd, Jerome
core  

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

PEG: Will It Come Back to You? Polyethelyne Glycol Immunogenicity, COVID Vaccines, and the Case for New PEG Derivatives and Alternatives

Frontiers in Bioengineering and Biotechnology, 2022
Yi Wen Kong, Yi Wen Kong, Erik C Dreaden, Erik C Dreaden, Erik C Dreaden, Erik C Dreaden, Erik C Dreaden   +6 more
doaj   +1 more source

Efficient and thermally stable organic solar cells based on small molecule donor and polymer acceptor

Nature Communications, 2019
The organic solar cells are typically based on a binary combination of polymeric donor and molecular acceptor. Here Zhang et al. develop alternative combination based on molecular donor and polymeric acceptor featuring 8% efficiency and high stability up
Zijian Zhang, Junhui Miao, Zicheng Ding, Bin Kan, Baojun Lin, Xiangjian Wan, Wei Ma, Yongsheng Chen, Xiaojing Long, Chuandong Dou, Jidong Zhang, Jun Liu, Lixiang Wang   +12 more
doaj   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Polymeric Switch on Lysozyme Activity: Role of Hydrophobic and Electrostatic Interactions

Journal of Pure and Applied Chemistry Research, 2013
Enzymes have attracted potential applications in both medicine and biotechnology. In our present study, we show a strategy for switching the enzymatic activity of lysozyme by the complex formation with a cationic smart copolymer.
Dr. Sumon Ganguli, Md. Bellal Hossain
doaj  

Recent advances in the synthesis of polymer supported catalysts: a review

Discover Applied Sciences
Heterogenous catalysis plays a crucial role in organic synthesis, and over the past years, it has undergone significant progress. Further, polymer-supported catalysts have been introduced successfully in various organic transformations.
C. H. Raksha, M. P. Yogeesh, Nitinkumar S. Shetty   +2 more
doaj   +1 more source

Experimental Design in Polymer Chemistry-A Guide towards True Optimization of a RAFT Polymerization Using Design of Experiments (DoE). [PDF]

Polymers (Basel), 2021
Eckert T, Klein FC, Frieler P, Thunich O, Abetz V.   +4 more
europepmc   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source